Ingredient Dictionary

CI 16185

Amaranth is an organic molecular entity.

Definition

Amaranth is an organic molecular entity.

Source: PubChem

US FDA substance register · UNII 37RBV3X49K · registered name AMARANTH · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

CI 16185 is classed chemically as a monoazo colour. It conforms to the formula:

Cosmetic roles

Adds colourCOLORANTDyes hairHAIR DYEING

Safety & regulatory references

Banned: ASEAN · European Union · United Kingdom
Restricted or banned: ASEAN · European Union · Taiwan
Restricted: ASEAN · China · European Union · Japan · South Korea · Taiwan
Allowed colourant: ASEAN · Taiwan · United States

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS) · Taiwan FDA cosmetic ingredients · US FDA prohibited and restricted ingredients

Argentina · Brazil

Field of application and/or use : Dye Substances allowed for all kinds of products.

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex II (prohibited substances), entry 1350

Source: EU prohibited substances (Annex II)

Restriction II/1350 (Acid Red 27; CI 16185: when used as a substance in hair dye products)

Source: EU CosIng ingredient list

Restriction IV/33 (CI 16185) II/1350 (Acid Red 27; CI 16185: when used as a substance in hair dye products)

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name 赤２: 本品は、昭和41年厚生省令第30号に示される赤色２号又はそのアルミニウムレーキである。

Source: JCIA labelling names (Japan)

Names & identifiers

CI 16185INCI적색2호Korean label name (MFDS standard)산성적색27호Korean label name (MFDS standard)2,7-Naphthalenedisulfonic acid, 3-hydroxy-4-[(4-sulfo-1-naphthalenyl)azo]-, trisodium saltSynonymACID RED 27Synonym赤２Japanese labelling name

CAS No.chemical registry number: 915-67-3
EC No.EU chemical inventory number: 213-022-2
DTXSIDUS EPA chemical ID: DTXSID2021232
DTXCIDUS EPA compound ID: DTXCID801856244

IUPAC: Trisodium 3-hydroxy-4-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-2,7-disulfonate
Molecular formula: C20H11N2Na3O10S3
Molecular weight: 604.46 g/mol

Measured properties

Appearance: solid
Melting/freezing point: ℃
Vapour pressure: 0.0000000000000000000000005.82 (at 25 C)
Relative density: 1.5g/cm3 (water=1)
Molecular weight: 604.48 g/mol

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 58 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Dye58

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 1 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 4 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
Skin sensitization - Category 1
Skin Sensitization · Screening
Corrosive or Irritation Persists for > 21 days
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 492 (Reconstructed Human Cornea-like Epithelium (RhCE) Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage) according to