CI 45100

CI 45100 is classed chemically as a xanthene colour. It conforms to the formula:

Lissamine rhodamine is an organic sodium salt having 4-[3,6-bis(diethylamino)xanthenium-9-yl]benzene-1,3-disulfonate as the counterion. It has a role as a fluorescent probe, a fluorochrome and a histological dye. It contains a lissamine rhodamine anion.

Source: PubChem

US FDA substance register · UNII 821LWZ3R6R · registered name ACID RED 52 · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Restricted

China · Japan · Taiwan · United Kingdom

Allowed colourant

Taiwan

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · Taiwan FDA cosmetic regulations · UK cosmetics regulations (OPSS)

Argentina · Brazil

• Field of application and/or use : Dye Substances allowed exclusively in products that have short time of skin and hair contact.

ASEAN

• Field of application and/or use : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
• Maximum authorised concentration in the finished cosmetic product : (b) 0.6%
• Other limitations and requirements : (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5 %. The free base and salts of this hair colouring ingredient, unless prohibited under Annex II, are permitted for use. The direction for use “wear suitable gloves” must be included in label or leaflet text.
• Conditions of use and warning which must be printed on the labels : (a)The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past (a) and (b) Do not use to dye eyelashes or eyebrows

South Korea

• Maximum concentration : 0.6%

European Union

• Product Type, body parts : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
• Maximum concentration in ready for use preparation : (b) 0.6%
• Other : (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5%.
• Wording of conditions of use and warnings : a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp,— you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.
• Product Type, body parts : Rinse-off products

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex IV (allowed colourants), entry 71 · maximum concentration Rinse-off products

Source: EU allowed colourants (Annex IV)

EU Cosmetics Regulation, Annex III (restricted substances), entry 193 · maximum concentration (b) 0.6% · applies to (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products

Source: EU restricted substances (Annex III)

Restriction III/193 IV/71 · Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Opinion on Acid Red 52

Source: EU CosIng ingredient list

Restriction IV/71 III/193 (Acid Red 52) · SCCS opinion: Opinion on Acid Red 52

Source: EU CosIng ingredient list