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成分词典

成分词典

CI 45100

CI 45100 is classed chemically as a xanthene colour.

韩国限量
0.6%
分子结构

产品中实际含有多少

暂无产品标示该成分含量。

含该成分的产品中,0 款将其列在 1% 线之前,1 款列在之后(通常不超过 1%)。

含有此成分的产品

已确认 1 款中的 1 款 · 按含量充足程度排序

定义

CI 45100 is classed chemically as a xanthene colour. It conforms to the formula:

Lissamine rhodamine is an organic sodium salt having 4-[3,6-bis(diethylamino)xanthenium-9-yl]benzene-1,3-disulfonate as the counterion. It has a role as a fluorescent probe, a fluorochrome and a histological dye. It contains a lissamine rhodamine anion.

来源: PubChem

美国FDA 物质登记 · UNII 821LWZ3R6R · 登记名称 ACID RED 52 · 单一化学物质

来源: 美国FDA 物质识别码(UNII)

化妆品中的作用

染发HAIR DYEING着色COLORANT

安全与法规参考

限用
日本 · 英国 · 中国

来源: 东盟化妆品指令 · 欧盟化妆品法规 · 韩国食药处 化妆品法规信息 · 台湾FDA 化妆品成分 · 台湾FDA 化妆品法规 · 英国化妆品法规

阿根廷 · 巴西

  • Field of application and/or use : Dye Substances allowed exclusively in products that have short time of skin and hair contact.

东盟

  • Field of application and/or use : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
  • Maximum authorised concentration in the finished cosmetic product : (b) 0.6%
  • Other limitations and requirements : (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5 %. The free base and salts of this hair colouring ingredient, unless prohibited under Annex II, are permitted for use. The direction for use “wear suitable gloves” must be included in label or leaflet text.
  • Conditions of use and warning which must be printed on the labels : (a)The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past (a) and (b) Do not use to dye eyelashes or eyebrows

台湾

  • ※ 染髮產品之限量標準:係指該成分依產品使用說明書混合後之最高允許使用量。
  • ※ 化粧品之外包裝或容器,應明顯標示本表所列成分之注意事項。因外包裝或容器表面積過小或其他特殊情形致不能標示者,應於標籤、仿單或以其他方式刊載之。
  • ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
  • ※ 化粧品宣稱效能者,須符合化粧品標示宣傳廣告涉及虛偽誇大或醫療效能認定準則規定。
  • 用途 : 使用限制
  • 最大配合量 : (a)氧化性染髮產品 : 1.5%
  • (b)非氧化性染髮產品 : 0.6%

韩国

  • 最大配合量 : 0.6%

欧盟

  • Product Type, body parts : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
  • Maximum concentration in ready for use preparation : (b) 0.6%
  • Other : (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5%.
  • Wording of conditions of use and warnings : a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp,— you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.
  • Product Type, body parts : Rinse-off products

来源: 韩国食药处 化妆品法规信息

未列入韩国有毒物质 GHS 分类 · 现有化学物质

来源: 韩国有毒物质 GHS 信息(环境公团)

欧盟化妆品法规 附录IV(准用着色剂) 第71项 · 最高浓度 Rinse-off products

来源: 欧盟准用着色剂(附录IV)

欧盟化妆品法规 附录III(限用物质) 第193项 · 最高浓度 (b) 0.6% · 适用 (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products

来源: 欧盟限用成分(附录III)

Restriction III/193 IV/71 · Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Opinion on Acid Red 52

来源: 欧盟 CosIng 成分清单

Restriction IV/71 III/193 (Acid Red 52) · SCCS opinion: Opinion on Acid Red 52

来源: 欧盟 CosIng 成分清单

详细资料——标示名称、识别编号、物性、试验记录、文献

官方标示名称和定义

日本化妆品工业联合会标示名称 赤106: 本品は、昭和41年厚生省令第30号に示される赤色106号又はそのアルミニウムレーキである。

来源: 日本化妆品工业联合会标示名称

别名和识别信息

CI 45100INCI적색106호韩国标示名称(食药处标准名)산성적색52호韩国标示名称(食药处标准名)Ethanaminium, N-[6-(diethylamino)-9-(2,4-disulfophenyl)-3H-xanthen-3-ylidene]-N-ethyl-, hydroxide, inner salt, sodium salt同义名ACID RED 52同义名赤106日本标示名称
CAS No.化学物质登记号
3520-42-1
EC No.欧盟化学品目录编号
222-529-8
DTXSID美国EPA化学品编号
DTXSID7021235
DTXCID美国EPA化合物编号
DTXCID601333854
IUPAC
Sodium 4-[3,6-bis(diethylamino)xanthen-10-ium-9-yl]benzene-1,3-disulfonate
分子式
C27H29N2NaO7S2
分子量
580.65 g/mol

实测物性

熔点/凝固点
349.84 ℃(估算值)
初沸点和沸程
1004.49 ℃(估算值)
蒸气压
0.000000000000000000000000000001 ㎜Hg (估算值)
溶解度
0.168 ㎎/ℓ (估算值)
正辛醇/水分配系数(Kow)
3.162 (估算值)
分子量
580.65

这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。

来源: 韩国安全保健公团 安全数据表

产品实际使用的用途

这是向美国 EPA 申报含该成分的 75 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。

  • Dye74
  • Fragrance1

来源: 美国EPA CompTox

刺激与致敏试验记录

记录有皮肤试验 3 项、眼部试验 2 项。

归类为低3 项

试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。

查看全部 5 项试验
  • Not likely to be sensitizing
    skin sensitisation: in vivo (LLNA) · Screening · equivalent or similar to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · other guideline: the Consumer Product Safety Commission of the U. S. A. in The Code of Federal Regulations, Tltle 16, Section 1500. 41 according to
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · other guideline: "Hazardous Substances Regulations" under the U.S. Federal Hazardous Substances Labelling Act Sect. 191.11 (February 1965). according to
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · other guideline: The Consumer Product Safety Commission of the U.S.A. in The Code of Federal Regulations, Title 16, Sectlon 1500.42 according to
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · other guideline: the procedure set out in the "Hazardous Substances Regulations" under the U.S.A. Federal Hazardous Substances Labelling Act Sect. 191.12 (February 1965), with slight modification according to

来源: 美国EPA CompTox

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