Ingredient Dictionary

CI 58000

Alizarin is a dihydroxyanthraquinone that is anthracene-9,10-dione in which the two hydroxy groups are located at positions 1 and 2.

Definition

Alizarin is a dihydroxyanthraquinone that is anthracene-9,10-dione in which the two hydroxy groups are located at positions 1 and 2. It has a role as a chromophore, a dye and a plant metabolite.

Source: PubChem

US FDA substance register · UNII 60MEW57T9G · registered name ALIZARIN · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

CI 58000 is classed chemically as an anthraquinone colour. It conforms to the formula:

Cosmetic roles

Dyes hairHAIR DYEINGAdds colourCOLORANT

Safety & regulatory references

Banned: Argentina · ASEAN · Brazil · European Union · United Kingdom
Restricted or banned: Argentina · ASEAN · Brazil · China · European Union · Taiwan
Allowed colourant: ASEAN · Taiwan · United States

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS) · Taiwan FDA cosmetic ingredients · US FDA prohibited and restricted ingredients

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex II (prohibited substances), entry 1361

Source: EU prohibited substances (Annex II)

EU Cosmetics Regulation, Annex IV (allowed colourants), entry 86

Source: EU allowed colourants (Annex IV)

Restriction II/1361 (when used as a substance in hair dye products)

Source: EU CosIng ingredient list

Restriction IV/86 (CI 58000) II/1361 (Pigment Red 83; CI 58000: when used as a substance in hair dye products)

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

CI 58000INCI피그먼트적색83호Korean label name (MFDS standard)9,10-Anthracenedione, 1,2-dihydroxy-SynonymPIGMENT RED 83Synonym

CAS No.chemical registry number: 104074-25-1; 72-48-0
CAS No.chemical registry number: 72-48-0
EC No.EU chemical inventory number: 200-782-5
DTXSIDUS EPA chemical ID: DTXSID5045960
DTXCIDUS EPA compound ID: DTXCID3025960

IUPAC: 1,2-Dihydroxyanthracene-9,10-dione
Molecular formula: C14H8O4
Molecular weight: 240.214 g/mol

Measured properties

Appearance: Red-orange crystals slightly soluble in water, [Sax] · solid
Boiling point: 430 °C @760 [mm Hg]
Melting point: 289 °C
Density: 1.54 @ 20°C
Melting/freezing point: 289.5 ℃
Initial boiling point and range: 430 ℃
Water solubility: 400 ㎎/ℓ (@ 0 ℃)
Vapour density: 8.29
Relative density: 1.54
n-Octanol/water partition coefficient (Kow): 3.160 (est.)
Molecular weight: 240.22

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Dye3

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 0 eye studies are on record.

Classed as moderate2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies

SkinSens1
Skin Sensitization · QSAR Predicted
SkinIrr2
Skin Irritation · QSAR Predicted