What is this ingredient?

미국 FDA 물질 등록 · UNII G5UX3K0728 · 등록명 EXT. D&C VIOLET NO. 2 · 단일 화학물질

All ingredients

Ingredient Dictionary

CI 60730

CI 60730 is classed chemically as an anthraquinone colour.

How much products actually contain

No product states its amount yet.

Of the products containing it, 101 list it before the 1% line and 18 after it (usually 1% or less).

Products using this ingredient

12 of 119 confirmed · likeliest to carry enough first · See all 119

Definition

US FDA substance register · UNII G5UX3K0728 · registered name EXT. D&C VIOLET NO. 2 · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

CI 60730 is classed chemically as an anthraquinone colour. It conforms to the formula:

Cosmetic roles

Dyes hairHAIR DYEINGAdds colourCOLORANT

Safety & regulatory references

Restricted: Japan · South Korea · Taiwan · United Kingdom · United States
Allowed colourant: Taiwan · United States

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · Taiwan FDA cosmetic regulations · UK cosmetics regulations (OPSS) · US FDA prohibited and restricted ingredients

Argentina · Brazil

Field of application and/or use : Dye Substances allowed exclusively in products that do not have contact with mucosa in regular and predictable use conditions.

ASEAN

Field of application and/or use : Hair dye substance in oxidative hair dye products. Use for dyeing eyelashes and eyebrows is not permitted.
Maximum authorised concentration in the finished cosmetic product : (b) 0.5%
Other limitations and requirements : The direction for use “wear suitable gloves” must be included in label or leaflet text.
Conditions of use and warning which must be printed on the labels : Do not use to dye eyelashes or eyebrows

China

Maximum concentration : 1%

European Union

Product Type, body parts : Hair dye substance in non-oxidative hair dye products
Maximum concentration in ready for use preparation : 0,5 %

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex IV (allowed colourants), entry 90 · maximum concentration Not to be used in products applied on the mucous membranes

Source: EU allowed colourants (Annex IV)

EU Cosmetics Regulation, Annex III (restricted substances), entry 291 · maximum concentration 0,5 % · applies to Hair dye substance in non-oxidative hair dye products

Source: EU restricted substances (Annex III)

Restriction III/291 · Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Opinion on Acid Violet 43

Source: EU CosIng ingredient list

Restriction IV/90

Source: EU CosIng ingredient list

Reviewed by CIR: Final Report: Amended Safety Assessment of Acid Violet 43 as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Acid Violet 43

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Names & identifiers

CI 60730INCI자색401호Korean label name (MFDS standard)산성자색43호Korean label name (MFDS standard)Benzenesulfonic acid, 2-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthracenyl)amino]-5-methyl-, sodium salt (1:1)SynonymACID VIOLET 43Synonym

CAS No.chemical registry number: 4430-18-6
EC No.EU chemical inventory number: 224-618-7
DTXSIDUS EPA chemical ID: DTXSID6041717
DTXCIDUS EPA compound ID: DTXCID4021717

IUPAC: Sodium 2-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-5-methylbenzene-1-sulfonate
Molecular formula: C21H14NNaO6S
Molecular weight: 431.39 g/mol

Measured properties

Flash point: 185.3 ℃
Flammability (solid, gas): not flammable
Vapour pressure: 0.012 ㎩ (45℃)
Water solubility: 1708 ㎎/ℓ (20℃, pH: 11.7)
Relative density: 1.64
n-Octanol/water partition coefficient (Kow): -0.66 (log Pow, 22℃)
Auto-ignition temperature: 241.8 ℃
Molecular weight: 431.4

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 25 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Dye24
Fragrance1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 5 eye studies are on record.

Classed as low5

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 9 studies

Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: refer below principle
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: OECD 406 (1993) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: refer below principle according to
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) Adopted 24th April 2002
Corrosive or Irritation Persists for > 21 days
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage) according to
Studies Indicate No Significant Irritation
eye irritation: in vitro / ex vivo · Screening · other guideline: refer below principle according to
Ambiguous
eye irritation: in vivo · Screening · other guideline: Recommendations of the Journal Officiel de la Republique Francaise of 21/4/71 and 5/6/73 according to
Ambiguous
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) Adopted : 24th April 2002 according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) EC Directive No. 92/69/EEC, B.5, 31st July 1992 according to
Moderate or Mild Irritation
eye irritation: in vitro / ex vivo · Screening · other guideline: refer below principle according to