What is this ingredient?

미국 FDA 물질 등록 · UNII NJN999RX4C · 등록명 C.I. Pigment Orange 43 · 단일 화학물질

All ingredients

Ingredient Dictionary

CI 71105

CI 71105 is classed chemically as an indigoid colour.

Definition

US FDA substance register · UNII NJN999RX4C · registered name C.I. Pigment Orange 43 · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

CI 71105 is classed chemically as an indigoid colour. It conforms to the formula:

Cosmetic roles

Adds colourCOLORANT

Safety & regulatory references

Restricted: ASEAN · China · Taiwan
Allowed colourant: ASEAN · Taiwan · United Kingdom

Source: MFDS (Korea) cosmetic regulatory information · ASEAN Cosmetic Directive · EU Cosmetics Regulation · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)

Argentina · Brazil

Field of application and/or use : Dye Substances allowed exclusively in products that do not have contact with mucosa in regular and predictable use conditions.

European Union

Product Type, body parts : Not to be used in products applied on mucous membranes

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex IV (allowed colourants), entry 97 · maximum concentration Not to be used in products applied on mucous membranes

Source: EU allowed colourants (Annex IV)

Restriction IV/97

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

CI 71105INCIBisbenzimidazo[2,1-b:2',1'-i]benzo[lmn][3,8]phenanthroline-8,17-dioneSynonym

CAS No.chemical registry number: 4424-06-0
EC No.EU chemical inventory number: 224-597-4
DTXSIDUS EPA chemical ID: DTXSID8025913
DTXCIDUS EPA compound ID: DTXCID805913

IUPAC: Bis[1,3]benzimidazo[2,1-b:2',1'-i]benzo[lmn][3,8]phenanthroline-8,17-dione
Molecular formula: C26H12N4O2
Molecular weight: 412.408 g/mol

Measured properties

Appearance: solid
Vapour density: 14.2
n-Octanol/water partition coefficient (Kow): 4.58
Molecular weight: 412.399080

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Pigment5
Dye1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to