Quinacridone is an organonitrogen heterocyclic compound and an organic heterotetracyclic compound.
Definition
Quinacridone is an organonitrogen heterocyclic compound and an organic heterotetracyclic compound.
Source: PubChem
US FDA substance register · UNII 11P487375P · registered name CINQUASIA RED · single chemical substance
CI 73900 is classed chemically as a quinacridone colour. It conforms to the formula:
Cosmetic roles
Safety & regulatory references
- Banned
- Argentina · ASEAN · Brazil · European Union · United Kingdom
- Restricted or banned
- Argentina · ASEAN · Brazil · China · European Union · Taiwan
- Allowed colourant
- ASEAN · Taiwan
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS) · Taiwan FDA cosmetic ingredients
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
EU Cosmetics Regulation, Annex II (prohibited substances), entry 1366
EU Cosmetics Regulation, Annex IV (allowed colourants), entry 102 · maximum concentration Rinse-off products
Source: EU allowed colourants (Annex IV)
Restriction II/1366
Source: EU CosIng ingredient list
Restriction IV/102 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 1047-16-1
- EC No.EU chemical inventory number
- 213-879-2
- DTXSIDUS EPA chemical ID
- DTXSID5027354
- DTXCIDUS EPA compound ID
- DTXCID407354
- IUPAC
- 5,12-Dihydroquinolino[2,3-b]acridine-7,14-dione
- Molecular formula
- C20H12N2O2
- Molecular weight
- 312.328 g/mol
Measured properties
- Appearance
- Liquid, Other Solid, Dry Powder, CBI · Red to violet solid, Bluish or yellowish tint depending of form, [HSDB] Red odorless powder, [MSDSonline]
- Melting point
- 390 °C
- Solubility
- Insoluble in water · Insoluble in organic solvents and dispersion media.
- Density
- 1.5
- Stability
- Stable up to 165 °C
- pH
- 7-8
- Melting/freezing point
- 390 ℃
- Relative density
- 1.5
- n-Octanol/water partition coefficient (Kow)
- 1.9 (est.)
- Decomposition temperature
- 350 ℃
- Molecular weight
- 312.18
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 29 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Pigment21
- Dye6
- Processing aids not otherwise specified2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
6 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 9 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to EU Method B.6 (Skin Sensitisation) according to OECD Guideline 406 (Skin Sensitisation) - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EU Method B.6 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: EPA-TSCA 40 CFR 798 according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: FDA guideline (Federal Register 38, No. 187, 27.9.1973) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: EPA-TSCA 40 CFR 798 according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: FDA guideline (Federal Register 38, No. 187, 27.9.1973) according to
Source: US EPA CompTox dashboard
Linked databases 21
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- China inventory of existing ingredients (IECIC)
- EU allowed colourants (Annex IV)
- EU CosIng ingredient list 2 3
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3 4
- NIST Chemistry WebBook
- PubChem 2
- Taiwan FDA cosmetic ingredients
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata 2