定义
美国FDA 物质登记 · UNII 50MD4SB4AP · 登记名称 CICLOPIROX OLAMINE · 单一化学物质
化妆品中的作用
抑制微生物生长ANTIMICROBIAL作用于脂溢性皮屑和头屑ANTI-SEBORRHEIC
安全与法规参考
- 限用·禁用
- 韩国 · 中国
来源: 韩国食药处 化妆品法规信息
阿根廷 · 巴西
- Maximum concentration permitted at final product : Under maximum secondary amine: 0.5%
- Other limitations and requirements : No use with nitrosating systems. Minimum 99% -Pureza. Maximum -Tenor of secondary amines in raw materials 0.5%. Maximum nitrosamine -Tenor: 50 ug / kg. -Envasar / Nitrite - free store in containers.
东盟
- Maximum authorised concentration in the finished cosmetic product : Maximum secondary amine content: 0.5%
- Other limitations and requirements : • Do not use with nitrosating systems • Minimum purity: 99% • Maximum secondary amine content: 0.5% (applies to raw materials) • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers
欧盟
- Maximum concentration in ready for use preparation : Maximum secondary amine content: 0.5%
- Other : - Do not use with nitrosating systems - Minimum purity: 99% - Maximum secondary amine content: 0.5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers
来源: 韩国食药处 化妆品法规信息
Restriction III/61
来源: 欧盟 CosIng 成分清单
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
CICLOPIROX OLAMINEINCI시클로피록스올아민韩国标示名称(食药处标准名)
- CAS No.化学物质登记号
- 41621-49-2
- EC No.欧盟化学品目录编号
- 255-464-9
- DTXSID美国EPA化学品编号
- DTXSID6045583
- DTXCID美国EPA化合物编号
- DTXCID4025583
- IUPAC
- 6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one--2-aminoethan-1-ol (1/1)
- 分子式
- C14H24N2O3
- 分子量
- 268.357 g/mol
产品实际使用的用途
这是向美国 EPA 申报含该成分的 2 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Anti-dandruff (EPA)1
- Biocide1
来源: 美国EPA CompTox
相关文献
- Comparative Efficacy of Oxiconazole Cream Versus Ciclopirox Olamine Cream in the Management of Localized Cutaneous Dermatophytosis: A Randomized Controlled Trial. · 2026
- Modeling, the Optimization of the Composition of Emulgels with Ciclopirox Olamine, and Quality Assessment · 2024
- Antifungal drug ciclopirox olamine reduces HSV‐1 replication and disease in mice · 2018
- Transdermal Delivery of Ciclopirox Olamine via Ethosomal and Liposomal Carrier · 2011
- Allergic contact dermatitis from ciclopirox olamine. · 2001