Ingredient Dictionary

CINEOLE

1,4-cineole is an oxabicycloalkane consisting of p-menthane with an epoxy bridge across positions 1 and 4.

Definition

1,4-cineole is an oxabicycloalkane consisting of p-menthane with an epoxy bridge across positions 1 and 4. It has a role as a central nervous system depressant, a fumigant insecticide and a plant metabolite. It is a cineole and an oxabicycloalkane.

Source: PubChem

US FDA substance register · UNII B55JTU839B · registered name 1,4-CINEOLE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Protects skin from outside irritantsSKIN PROTECTINGGives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name シネオール: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

CINEOLEINCI시네올Korean label name (MFDS standard)7-Oxabicyclo[2.2.1]heptane, 1-methyl-4-(1-methylethyl)-SynonymシネオールJapanese labelling name

CAS No.chemical registry number: 470-67-7
EC No.EU chemical inventory number: 207-428-9
DTXSIDUS EPA chemical ID: DTXSID3047396
DTXCIDUS EPA compound ID: DTXCID201473981

IUPAC: (1s,4s)-1-Methyl-4-(propan-2-yl)-7-oxabicyclo[2.2.1]heptane
Molecular formula: C10H18O
Molecular weight: 154.253 g/mol

Measured properties

Appearance: Liquid · liquid
Boiling point: 65.00 °C. @ 16.00 mm Hg
Melting point: 1 °C
Colour: colourless
Vapour pressure: 1.93 (ChemIDPlus)
Molecular weight: 154.26

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 19 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance16
Flavouring and nutrient2
Humectant1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 1 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies

Category 6.3A (Category 2)
Skin Irritation · Read Across
Category 6.4A (Category 2A)
Eye Irritation · Read Across