Ingredient Dictionary

CINNAMAL

(E)-cinnamaldehyde is the E (trans) stereoisomer of cinnamaldehyde, the parent of the class of cinnamaldehydes.

How much products actually contain

No product states its amount yet.

Of the products containing it, 13 list it before the 1% line and 17 after it (usually 1% or less).

Products using this ingredient

12 of 30 confirmed · likeliest to carry enough first · See all 30

Definition

(E)-cinnamaldehyde is the E (trans) stereoisomer of cinnamaldehyde, the parent of the class of cinnamaldehydes. It has a role as a sensitiser, a hypoglycemic agent, a flavouring agent, a vasodilator agent, an antifungal agent, an EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitor and a plant metabolite. It is a 3-phenylprop-2-enal and a member of cinnamaldehydes.

Source: PubChem

US FDA substance register · UNII SR60A3XG0F · registered name CINNAMALDEHYDE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Adds flavour (lip and oral products)FLAVOURINGMakes alcohol undrinkableDENATURANTGives the product a scentPERFUMING

Safety & regulatory references

Restricted: International fragrance standard (IFRA) · United Kingdom

Source: EU Cosmetics Regulation · IFRA fragrance standards · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)

European Union

Other : The presence of the substance must be indicated in the list of ingredients referred to in Article 6(1)g when its concentration exceeds: - 0.001% in leave-on products - 0.01% in rinse-off products

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex III (restricted substances), entry 76

Source: EU restricted substances (Annex III)

Restriction III/76 · Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Cinnamal, Cinnamyl Acetate, Cinnamyl Alcohol, Amyl Cinnamal and Amylcinnamyl Alcohol (defer to RIFM review)

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ケイヒアルデヒド: 本品は、次の化学式で表される芳香族アルデヒドである。

Source: JCIA labelling names (Japan)

Names & identifiers

CINNAMALINCI신남알Korean label name (MFDS standard)2-Propenal, 3-phenyl-SynonymケイヒアルデヒドJapanese labelling name

CAS No.chemical registry number: 104-55-2
EC No.EU chemical inventory number: 203-213-9
DTXSIDUS EPA chemical ID: DTXSID1024835
DTXCIDUS EPA compound ID: DTXCID904835

IUPAC: 3-Phenylprop-2-enal
Molecular formula: C9H8O
Molecular weight: 132.162 g/mol

Measured properties

Appearance: CBI, Other Solid, Liquid · Yellowish oily liquid, [HSDB]
Odour: PUNGENT, SPICY NOTE · Strong odor of cinnamon
Boiling point: 253 °C @ 760 MM HG (SLIGHT DECOMP) · 248.00 °C. @ 760.00 mm Hg
Melting point: -7.5 °C
Solubility: Dissolves in about 700 parts water, in about 7 volumes of 60% alcohol. · SOL IN ETHER, CHLOROFORM, INSOL IN PETROLEUM ETHER
Density: 1.048-1.052 at 25 °C/25 °C · 1.046-1.053
Melting/freezing point: -8 ℃
Initial boiling point and range: 246~253 ℃
Flash point: 111 ℃
Vapour pressure: 0.02 ㎜Hg (at 20℃)
Water solubility: 1420 ㎎/ℓ
Vapour density: 4.5-4.6
Relative density: 1.048-1.052
n-Octanol/water partition coefficient (Kow): 1.9
Molecular weight: 289.30

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 374 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance357
Flavouring and nutrient11
Processing aids not otherwise specified3
Deodorizer2
Anti-scaling agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

10 skin studies and 0 eye studies are on record.

Classed as highly irritating7

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 10 studies

High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline:
High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Principle mentioned below
Category 6.5B (Category 1)
Skin Sensitization · Read Across
SkinSens1
Skin Sensitization · QSAR Predicted
SkinIrr2
Skin Irritation · QSAR Predicted
Sh
Skin Sensitization · Authoritative
Category 6.3A (Category 2)
Skin Irritation · Read Across
Severe Irritation
skin irritation: in vivo · Screening · other guideline: according to
High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: ICDRG guidelines
High Frequency of Sensitization
skin sensitisation · Screening · according to other guideline: Principle mentioned below