Definition
US FDA substance register · UNII D6S4O4XD0H · registered name CROTAMITON · mixture
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 483-63-6
- EC No.EU chemical inventory number
- 207-596-3
- DTXSIDUS EPA chemical ID
- DTXSID6040664
- DTXCIDUS EPA compound ID
- DTXCID4020664
- IUPAC
- N-Ethyl-N-(2-methylphenyl)but-2-enamide
- Molecular formula
- C13H17NO
- Molecular weight
- 203.285 g/mol
Measured properties
- Appearance
- Solid · liquid
- Boiling point
- 154 °C at 1.30E+01 mm Hg
- Melting point
- < 25 °C
- Solubility
- 3.53e-01 g/L
- Melting/freezing point
- &, lt, 25 ℃
- Molecular weight
- 203.29 (est.)
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent1
- Biocide1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- SkinSens1
Skin Sensitization · QSAR Predicted
Source: US EPA CompTox dashboard
Related literature
- Comparison Of Efficacy Of Permethrin 5% Cream With Crotamiton 10% Cream In Patients With Scabies. · 2019
- Comparative Efficacy of Topical Pertmehrin, Crotamiton and Sulfur Ointment in Treatment of Scabies · 2017
- Topical ivermectin versus crotamiton cream 10% for the treatment of scabies · 2014
- Treatment of scabies, permethrin 5% cream vs. crotamiton 10% cream. · 2013
- Percutaneous Absorption of Crotamiton in Man Following Single and Multiple Dosing · 2006
Linked databases 17
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese