Cucurbitacin B is a cucurbitacin in which a lanostane skeleton is multi-substituted with hydroxy, methyl and oxo substituents, with unsaturation at positions 5 and 23; a hydroxy function at C-25 is acetylated.
Definición
Cucurbitacin B is a cucurbitacin in which a lanostane skeleton is multi-substituted with hydroxy, methyl and oxo substituents, with unsaturation at positions 5 and 23; a hydroxy function at C-25 is acetylated. It is a tertiary alpha-hydroxy ketone, a cucurbitacin and a secondary alpha-hydroxy ketone. It derives from a hydride of a lanostane.
Fuente: PubChem
Registro de sustancias de la FDA (EE. UU.) · UNII 0115W5MABF · nombre registrado CUCURBITACIN B · sustancia química única
Fuente: Identificador único de ingredientes de la FDA (UNII)
Funciones cosméticas
Más datos: nombres, identificadores, propiedades, ensayos y literatura
Nombres e identificadores
- CAS No.número de registro químico
- 6199-67-3
- DTXSIDidentificador químico de la EPA (EE. UU.)
- DTXSID501316196
- DTXCIDidentificador de compuesto de la EPA (EE. UU.)
- DTXCID401746059
- IUPAC
- (2S,4R,23E)-2,16alpha,20-Trihydroxy-9alpha,10,14-trimethyl-1,11,22-trioxo-8beta-4,9-cyclo-9,10-secocholesta-5,23-dien-25-yl acetate
- Fórmula molecular
- C32H46O8
- Peso molecular
- 558.712 g/mol
Propiedades medidas
- Aspecto
- Solid, [Merck Index] · CRYSTALS FROM ABSOLUTE ETHANOL
- Punto de fusión
- 184-186 °C
Valores medidos en la sustancia en sí, no una especificación de una materia prima comercial.
Fuente: PubChem
Literatura relacionada
- Reduction of Cancer Stem Cells and Invasiveness of Human Melanoma and Breast Cancer by Cucurbitacin B from Lagenaria siceraria · 2023
- Cucurbitacin B, Purified and Characterized From the Rhizome of Corallocarpus epigaeus Exhibits Anti-Melanoma Potential · 2022
- Development and Evaluation of Cucurbitacin B Microemulsion: the Effect of Oil Phase and Aqueous Phase on Drug Percutaneous Absorption Based on ATR-FTIR Spectroscopy and Molecular Modeling · 2020
- Cucurbitacin B Induces the Lysosomal Degradation of EGFR and Suppresses the CIP2A/PP2A/Akt Signaling Axis in Gefitinib-Resistant Non-Small Cell Lung Cancer · 2019
- Cucurbitacin B suppresses proliferation of pancreatic cancer cells by ceRNA: Effect of miR‐146b‐5p and lncRNA‐AFAP1‐AS1 · 2018
Bases de datos vinculadas 12
- Búsqueda bibliográfica Tlooto 2 3 4 5
- ChEBI
- ChEMBL
- Diccionario de ingredientes de la Asociación Coreana de Cosméticos
- Identificador único de ingredientes de la FDA (UNII)
- Identificadores cruzados UniChem
- Lista de ingredientes CosIng (UE) 2
- Panel CompTox de la EPA
- PubChem 2
- Registro de ingredientes cosméticos del MFDS (Corea) 2
- Registro de sustancias de la FDA (GSRS)
- Wikidata