Cyclohexane is an alicyclic hydrocarbon comprising a ring of six carbon atoms; the cyclic form of hexane, used as a raw material in the manufacture of nylon.
How much products actually contain
No product states its amount yet.
Of the products containing it, 1 list it before the 1% line and 2 after it (usually 1% or less).
Products using this ingredient
3 of 3 confirmed · likeliest to carry enough first
Definition
Cyclohexane is an alicyclic hydrocarbon comprising a ring of six carbon atoms; the cyclic form of hexane, used as a raw material in the manufacture of nylon. It has a role as a non-polar solvent. It is a volatile organic compound and a cycloalkane.
Source: PubChem
US FDA substance register · UNII 48K5MKG32S · registered name Cyclohexane · single chemical substance
Cosmetic roles
Safety & regulatory references
Korea’s toxic-substance GHS classification: Danger · H315 (category 2) · H304 (category 1) · H400 (category 1) · +2 more
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name シクロヘキサン: 本品は、次の化学式で表される脂肪族炭化水素である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 110-82-7
- EC No.EU chemical inventory number
- 203-806-2
- DTXSIDUS EPA chemical ID
- DTXSID4021923
- DTXCIDUS EPA compound ID
- DTXCID701923
- IUPAC
- Cyclohexane
- Molecular formula
- C6H12
- Molecular weight
- 84.162 g/mol
Measured properties
- Appearance
- Cyclohexane appears as a clear colorless liquid with a petroleum-like odor. Used to make nylon, as a solvent, paint remover, and to make other chemicals. Flash point -4 °F. Density 6.5 lb / gal (less than water) and insoluble in water. Vapors heavier than air. · Large Crystals, Gas Vapor, Liquid
- Odour
- Solvent odor, pungent when impure · Pungent petroleum-like odor
- Boiling point
- 177.3 °F at 760 mmHg (NTP, 1992) · 80.7 °C at 760 mm Hg
- Melting point
- 43.7 °F (NTP, 1992) · 6.47 °C
- Solubility
- less than 1 mg/mL at 63 °F (NTP, 1992) · In water, 55 mg/L at 25 °C
- Density
- 0.779 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.7781 at 20 °C/4 °C
- Colour
- colourless
- Melting/freezing point
- 6.5 ℃
- Initial boiling point and range
- 80.7 ℃
- Flash point
- -20 ℃
- Evaporation rate
- 2.6
- Upper/lower flammability or explosive limits
- 8.4 / 1.3 %
- Vapour pressure
- 10.3 ㎪(20℃)
- Water solubility
- 0.07999 g/ℓ(25 ℃)
- Relative density
- 0.07739
- n-Octanol/water partition coefficient (Kow)
- 3.4
- Auto-ignition temperature
- 260 ℃
- Viscosity
- 0.894 cP(25℃)
- Molecular weight
- 84.16
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 84 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent50
- Degradant/impurity (EPA)9
- Defoamer8
- Fuel4
- Processing aids not otherwise specified4
- Intermediate3
- Monomers2
- Corrosion inhibitor1
3 other uses
- Fragrance1
- Catalyst1
- Cleaning agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
7 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 9 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to EU Method B.6 (Skin Sensitisation) - Skin corrosion/irritation - Category 2
Skin Irritation · Screening - Skin Irrit. 2
Skin Irritation · Authoritative - Category 6.3B (Category 3)
Skin Irritation · Read Across - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) equivalent or similar to - Classification not possible
Skin Sensitization · Screening - Category 2
Skin Irritation · Screening - Category 2
Eye Irritation · Screening - Moderate or Mild Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
- Experimental Investigation into the Extraction of Nicotinic Acid Using Natural Non-Toxic and Conventional Solvents · 2025
- Evaluation of two lipid removal methods for stable carbon and nitrogen isotope analysis in whale tissue. · 2020
- EFFECTS OF ENAMINOTHIONES COMPOUNDS ON THE DERMATOPHYES AND YEAST ISOLATES IN VITRO · 2017
- Atividade antibacteriana in vitro do extrato de Abarema cochliacarpos (Gomes) Barneby & J.W. Grimes contra bactérias isoladas de feridas cutâneas de cães · 2016
- Use of alcoholic waste as cyclohexane oxidation · 2013
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese