Dodecamethylcyclohexasiloxane is an organosilicon compound.
产品中实际含有多少
暂无产品标示该成分含量。
含该成分的产品中,563 款将其列在 1% 线之前,68 款列在之后(通常不超过 1%)。
含有此成分的产品
已确认 616 款中的 12 款 · 按含量充足程度排序 · 查看全部 616 款
HYGGEEFresh Vegan Tone-up Sun Cream
Elizabeth ArdenElizabeth Arden Flawless Finish Skincaring Foundation
LUVUMBamboo Hyaluronic Acid Moisture Sun Cream 50ml
CURLYSHYLLSilky Oil Serum 70ml
AbibHeartleaf Cream Calming Tube 75ml
Briall HommeNW Natural Whitening Tone-up Cream 50ml
SOME BY MIRetinol Intense Reactivating Serum
Dr. OracleDr. Oracle 21STAY A-Tera Cream
COSNORICOSNORI Avocado Eye Cream 30ml
COSNORICOSNORI Avocado Eye Cream 15ml
SOME BY MISOME BY MI Retinol Intense Reactivating Serum 30ml
SOME BY MISOME BY MI Retinol Intense Reactivating Serum 50ml
定义
美国FDA 物质登记 · UNII XHK3U310BA · 登记名称 CYCLOMETHICONE 6 · 单一化学物质
Dodecamethylcyclohexasiloxane is an organosilicon compound.
来源: PubChem
Cyclohexasiloxane is the cyclic dimethyl polysiloxane that conforms to the formula, where n equals 6, and the other components of cyclomethicone (where n equals 4, 5, or 7) are present at levels of less than 1%.
化妆品中的作用
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质 · 重点管理物质
Restriction Restricted under COMMISSION REGULATION (EU) 2024/1328. 1. Shall not be placed on the market (a) as a substance on its own; (b) as a constituent of other substances; or (c) in mixtures; in a concentration equal to or greater than 0,1 % by weight of the respective substance after 6 June 2026. [...] 3. By way of derogation: (a) for D4 and D5 in wash-off cosmetic products, paragraph 1, point (c), shall apply after 31 January 2020. For the purposes of this point, “wash-off cosmetic products” means cosmetic products as defined in Article 2(1), point (a), of Regulation (EC) No 1223/2009 of the European Parliament and of the Council (*1) that, under normal conditions of use, are washed off with water after application; (b) for all cosmetic products other than the ones mentioned in paragraph 3(a), paragraph 1 shall apply after 6 June 2027.
来源: 欧盟 CosIng 成分清单
Reviewed by CIR: Safety assessment of Cyclomethicone, Cyclotetrasiloxane, Cyclopentasiloxane, Cyclohexasiloxane and Cycloheptasiloxane
来源: 美国CIR 安全性评估
详细资料——标示名称、识别编号、物性、试验记录、文献
官方标示名称和定义
日本化妆品工业联合会标示名称 シクロヘキサシロキサン: 本品は、環状ポリシロキサンであり、次の化学式で表される。
来源: 日本化妆品工业联合会标示名称
别名和识别信息
- CAS No.化学物质登记号
- 540-97-6
- EC No.欧盟化学品目录编号
- 208-762-8
- DTXSID美国EPA化学品编号
- DTXSID6027183
- DTXCID美国EPA化合物编号
- DTXCID507183
- IUPAC
- Dodecamethylcyclohexasiloxane
- 分子式
- C12H36O6Si6
- 分子量
- 444.924 g/mol
实测物性
- 性状
- CBI, Liquid, Other Solid · Oily liquid
- 气味
- Odorless
- 沸点
- 245 °C
- 熔点
- -3 °C
- 溶解性
- In water, 0.0051 mg/L at 23 °C
- 密度
- 0.9672 g/cu cm at 25 °C
- 稳定性
- Stable under recommended storage conditions.
- 黏度
- 6.62 cSt · 5.66 ㎟/s(20 °C, QSAR)
- 熔点/凝固点
- -3.0 ℃
- 初沸点和沸程
- 245 ℃
- 闪点
- 91 ℃
- 蒸气压
- 0.0225 ㎜Hg( 25 ℃)
- 溶解度
- 0.0051 ㎎/ℓ( 25 ℃)
- 比重
- 0.9762
- 正辛醇/水分配系数(Kow)
- 6.33
- 自燃温度
- 368 ℃
- 分子量
- 44.93
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 36 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Softener and conditioner14
- Solvent5
- Degradant/impurity (EPA)3
- Intermediate3
- Diluent2
- Surfactant (surface active agent)2
- Lubricating agent2
- Dispersing agent2
其余用途 3 项
- Anti-adhesive/cohesive1
- Terminator/blocker1
- Viscosity modifier1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 2 项、眼部试验 1 项。
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 3 项试验
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
来源: 美国EPA CompTox
相关文献
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- Safety Assessment of Cyclomethicone, Cyclotetrasiloxane, Cyclopentasiloxane, Cyclohexasiloxane, and Cycloheptasiloxane · 2011