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Ingredients

Ingredient Dictionary

CYCLOHEXYLMETHACRYLATE

Molecular structure

Definition

US FDA substance register · UNII 5L9UUV9T6Q · registered name Cyclohexylmethacrylate · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cyclohexylmethacrylate is the organic compound that conforms to the formula

Cosmetic roles

Builds artificial nailsNAIL SCULPTING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Methacrylate Ester Monomers

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name メタクリル酸シクロヘキシル: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

CYCLOHEXYLMETHACRYLATEINCI사이클로헥실메타크릴레이트Korean label name (MFDS standard)2-Propenoic acid, 2-methyl-, cyclohexyl esterSynonymCYCLOHEXYL METHACRYLATESynonymメタクリル酸シクロヘキシルJapanese labelling name
CAS No.chemical registry number
101-43-9
EC No.EU chemical inventory number
202-943-5
DTXSIDUS EPA chemical ID
DTXSID7051507
DTXCIDUS EPA compound ID
DTXCID8030055
IUPAC
Cyclohexyl 2-methylprop-2-enoate
Molecular formula
C10H16O2
Molecular weight
168.236 g/mol

Measured properties

Appearance
liquid
Colour
colourless
Initial boiling point and range
210 ℃
Flash point
82 ℃
Vapour pressure
0.191 ㎜Hg(at 25C(est.))
Vapour density
5.8
Relative density
0.950 (at 20C)
n-Octanol/water partition coefficient (Kow)
3.13
Viscosity
5.0 cP(at 25C)
Molecular weight
168.24

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 7 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Monomers3
  • Solvent2
  • Intermediate1
  • Film former1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

5 skin studies and 4 eye studies are on record.

Classed as highly irritating1Classed as low1

The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 9 studies
  • Category 6.3B (Category 3)
    Skin Irritation · Read Across
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · other guideline: "Appraisal of the safety of chemicals in foods, drugs and cosmetics"; Division of Pharmacology, FDA; according to the Draize Test, 1959 according to
  • Category 1
    Skin Sensitization · Screening
  • Classification not possible
    Skin Irritation · Screening
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · other guideline: "Appraisal of the safety of chemicals in foods, drugs and cosmetics" Division of Pharmacology, FDA. According to Draize, 1959 according to
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across
  • Classification not possible
    Eye Irritation · Screening
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to

Source: US EPA CompTox dashboard

Related literature

Linked databases 16