Decursinol is an organic heterotricyclic compound that is 7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one substituted by a beta-hydroxy group at position 7 and two methyl groups at position 8.
定义
美国FDA 物质登记 · UNII UBI4YB704B · 登记名称 DECURSINOL · 单一化学物质
Decursinol is an organic heterotricyclic compound that is 7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one substituted by a beta-hydroxy group at position 7 and two methyl groups at position 8. It is isolated from the roots of Angelica gigas and has been found to possess significant inhibitory activity against acetylcholinesterase enzyme (EC 3.1.1.7). It has a role as a metabolite, an analgesic, an antineoplastic agent and an EC 3.1.1.7 (acetylcholinesterase) inhibitor. It is a delta-lactone, an organic heterotricyclic compound, a secondary alcohol and a cyclic ether.
来源: PubChem
化妆品中的作用
安全与法规参考
Other restriction: ban substances that deplete the ozone layer
来源: 欧盟 CosIng 成分清单
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 23458-02-8
- DTXSID美国EPA化学品编号
- DTXSID70178008
- DTXCID美国EPA化合物编号
- DTXCID60100499
- IUPAC
- (7S)-7-Hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one
- 分子式
- C14H14O4
- 分子量
- 246.262 g/mol
产品实际使用的用途
这是向美国 EPA 申报含该成分的 2 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Antioxidant1
- Softener and conditioner1
来源: 美国EPA CompTox
相关文献
- Decursinol Angelate Arrest Melanoma Cell Proliferation by Initiating Cell Death and Tumor Shrinkage via Induction of Apoptosis · 2021
- Decursinol angelate ameliorates 12-O-tetradecanoyl phorbol-13-acetate (TPA) -induced NF-κB activation on mice ears by inhibiting exaggerated inflammatory cell infiltration, oxidative stress and pro-inflammatory cytokine production. · 2019
- High-performance liquid chromatography determination and pharmacokinetics of coumarin compounds after oral administration of Samul-Tang to rats · 2014
- Cosmetic Effect of Angelica gigas Nakai Root Extracts · 2009