2'-deoxyguanosine is a purine 2'-deoxyribonucleoside having guanine as the nucleobase.
Definition
2'-deoxyguanosine is a purine 2'-deoxyribonucleoside having guanine as the nucleobase. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a purines 2'-deoxy-D-ribonucleoside and a purine 2'-deoxyribonucleoside. It is functionally related to a guanosine.
Source: PubChem
US FDA substance register · UNII G9481N71RO · registered name 2'-DEOXYGUANOSINE · single chemical substance
Deoxyguanosine is the organic compound that conforms to the formula:
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name デオキシグアノシン: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 961-07-9
- EC No.EU chemical inventory number
- 213-505-8
- DTXSIDUS EPA chemical ID
- DTXSID30883626
- DTXCIDUS EPA compound ID
- DTXCID401023136
- IUPAC
- 2'-Deoxyguanosine
- Molecular formula
- C10H13N5O4
- Molecular weight
- 267.245 g/mol
Measured properties
- Appearance
- solid
- Colour
- white
- Melting/freezing point
- 300 ℃
- Vapour pressure
- (2.75E-014㎜Hg, 25℃, est.)
- Water solubility
- 12000 ㎎/ℓ (25℃, est.)
- n-Octanol/water partition coefficient (Kow)
- -1.30
- Molecular weight
- 267.244
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
Source: US EPA CompTox dashboard
Related literature
- The Triplet State of 6‐thio‐2′‐deoxyguanosine: Intrinsic Properties and Reactivity Toward Molecular Oxygen · 2016
- Age- and sun exposure-dependent differences in 8-hydroxy-2'-deoxyguanosine and Nε-(carboxymethyl)lysine in human epidermis · 2011
- Mitochondrial DNA depletion can be prevented by dGMP and dAMP supplementation in a resting culture of deoxyguanosine kinase-deficient fibroblasts. · 2003
- Relevance of reactive oxygen species in the induction of 8-oxo-2'-deoxyguanosine in HaCaT keratinocytes. · 2002
- Induction and excretion of ultraviolet-induced 8-oxo-2'-deoxyguanosine and thymine dimers in vivo: implications for PUVA. · 2001
Linked databases 16
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese