Dequalinium chloride is an organic chloride salt that is the dichloride salt of dequalinium.
Definition
Dequalinium chloride is an organic chloride salt that is the dichloride salt of dequalinium. It has a role as an antineoplastic agent, an antifungal agent, a mitochondrial NADH:ubiquinone reductase inhibitor and an antiseptic drug. It contains a dequalinium.
Source: PubChem
US FDA substance register · UNII XYS8INN1I6 · registered name Dequalinium Chloride · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- South Korea
Source: MFDS (Korea) cosmetic regulatory information
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name 塩化デカリニウム: 本品は、次の化学式で表される４級アンモニウム塩である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 522-51-0
- EC No.EU chemical inventory number
- 208-330-9
- DTXSIDUS EPA chemical ID
- DTXSID3045144
- DTXCIDUS EPA compound ID
- DTXCID1025144
- IUPAC
- 1,1'-(Decane-1,10-diyl)bis(4-amino-2-methylquinolin-1-ium) dichloride
- Molecular formula
- C30H40Cl2N4
- Molecular weight
- 527.58 g/mol
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Deodorizer1
- Biocide1
- Pharmaceutical (EPA)1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Treatment of nonspecific vulvovaginitis in pregnant women: evaluation of the effectiveness of two-stage therapy · 2024
- Dequalinium chloride in the treatment of vaginal infections · 2023
- Pharmacotherapy for bacterial vaginosis: antibiotics vs antiseptics · 2023
- Empirical therapy as first-line treatment for vulvovaginal infections · 2022
- Evaluation of the effectiveness of dequalinium chloride vaginal tablets in aerobic vaginitis: A placebo-controlled study · 2021
Linked databases 15
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- MFDS (Korea) cosmetic regulatory information 2 3
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese