Butane-2,3-dione is an alpha-diketone that is butane substituted by oxo groups at positions 2 and 3.
定义
Butane-2,3-dione is an alpha-diketone that is butane substituted by oxo groups at positions 2 and 3. It is a metabolite produced during the malolactic fermentation. It has a role as a Saccharomyces cerevisiae metabolite and an Escherichia coli metabolite.
来源: PubChem
美国FDA 物质登记 · UNII K324J5K4HM · 登记名称 Diacetyl · 单一化学物质
化妆品中的作用
为产品增添香味PERFUMING
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
DIACETYLINCI2,3-Butanedione同义名
- CAS No.化学物质登记号
- 431-03-8
- EC No.欧盟化学品目录编号
- 207-069-8
- DTXSID美国EPA化学品编号
- DTXSID6021583
- DTXCID美国EPA化合物编号
- DTXCID701583
- IUPAC
- Butane-2,3-dione
- 分子式
- C4H6O2
- 分子量
- 86.09 g/mol
实测物性
- 性状
- Diacetyl appears as a clear colorless liquid with a strong chlorine-like odor. Flash point 80 °F. Less dense than water. Vapors heavier than air. · Clear liquid with a chlorine-like odor, [CAMEO]
- 气味
- Quinone odor, vapors have a chlorine-like odor · Very strong buttery odor in dilute solution
- 沸点
- 190 °F at 760 mmHg (NTP, 1992) · 87.5 °C
- 熔点
- 27.7 °F (NTP, 1992) · -1.2 °C
- 溶解性
- greater than or equal to 100 mg/mL at 72 °F (NTP, 1992) · In water, 200 g/L at 20 °C
- 密度
- 0.99 at 59 °F (NTP, 1992) - Less dense than water, will float · 0.990 at 15 °C/15 °C
- 稳定性
- Stable under recommended storage conditions.
- 熔点/凝固点
- -1.2 ℃
- 初沸点和沸程
- 88 ℃
- 闪点
- 6 ℃
- 蒸气压
- 56.8 ㎜Hg
- 溶解度
- (200 g/ℓ at 15 ℃)
- 蒸气密度
- 3.00 ( /Air = 1/)
- 比重
- 0.99 (at 15 ℃)
- 正辛醇/水分配系数（Kow）
- -1.34
- 自燃温度
- 365 ℃
- 分子量
- 86.09
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 6 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Flavouring and nutrient3
- Fragrance3
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 4 项、眼部试验 2 项。
归类为中等1 项
试验结论基本一致（100%）。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 6 项试验
- Category 2
Skin Irritation · Screening - Category 1
Skin Sensitization · Screening - Sh
Skin Sensitization · Authoritative - Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 1
Eye Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across
来源: 美国EPA CompTox
相关文献
- Minocycline and Diacetyl Minocycline Eye Drops Reduce Ocular Neovascularization in Mice · 2023
- Evaluation of diacetyl mediated pulmonary effects in physiologically relevant air-liquid interface models of human primary bronchial epithelial cells. · 2019
- The Diacetyl‐Exposed Human Airway Epithelial Secretome: New Insights into Flavoring‐Induced Airways Disease · 2017
- Fabrication and feasibility study of an absorbable diacetyl chitin surgical suture for wound healing. · 2016
- Combined use of two formulations containing diacetyl boldine, TGF‐β1 biomimetic oligopeptide‐68 with other hypopigmenting/exfoliating agents and sunscreen provides effective and convenient treatment for facial melasma. Either is equal to or is better than 4% hydroquinone on normal skin · 2016