Dibutyl adipate is a fatty acid ester.
How much products actually contain
No product states its amount yet.
Of the products containing it, 388 list it before the 1% line and 9 after it (usually 1% or less).
Products using this ingredient
12 of 390 confirmed · likeliest to carry enough first · See all 390
FROM THE SKINGlutathione Collagen Miracle Balm
innisfreeinnisfree Intensive Leisure Sun Stick SPF50+ PA++++
GROUNDPLANAqua Moisture Sun Stick
ModeloFresh Air-Fit Sun Stick
AnuaZero-cast Daily Invisible Moisture Sun Cream 50ml
AnuaHeartleaf Silky Moisture Sun Cream 50ml
ROUND LAB1025 Dokdo Sun Cream 50ml
ROUND LABPine Calming Cica Sun Cream 40ml
Dr.GSkin Boost PDRN Sun Serum 50ml
MEDIHEALMadecassoside Moisture Sun Serum Blemish Repair 50
MEDIHEALMadecassoside Moisture Sun Serum Blemish Repair 50
MEDIHEALMadecassoside Moisture Sun Serum Blemish Repair 50g
Definition
Dibutyl adipate is a fatty acid ester.
Source: PubChem
US FDA substance register · UNII F4K100DXP3 · registered name DIBUTYL ADIPATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Amended Final Report on the Safety Assessment of Dibutyl Adipate as used in Cosmetics
Reviewed by CIR: Final Report on the Safety Assessment of Dibutyl Adipate
Reviewed by CIR: Final Report of the Cosmetic Ingredient Review Expert Panel on the Safety Assessment of Dicarboxylic Acids, Salts and Esters
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name アジピン酸ジブチル: 本品は、アジピン酸（＊）とブタノール（＊）のジエステルであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 105-99-7
- EC No.EU chemical inventory number
- 203-350-4
- DTXSIDUS EPA chemical ID
- DTXSID2021866
- DTXCIDUS EPA compound ID
- DTXCID901866
- IUPAC
- Dibutyl hexanedioate
- Molecular formula
- C14H26O4
- Molecular weight
- 258.358 g/mol
Measured properties
- Appearance
- COLOURLESS LIQUID. · liquid
- Boiling point
- 183 °C
- Melting point
- -38 °C
- Solubility
- Solubility in water, g/100ml at 25 °C: 0.0035 (very poor)
- Density
- Relative density (water = 1): 0.96
- Melting/freezing point
- -38 ℃
- Initial boiling point and range
- 305 ℃
- Flash point
- 113 ℃
- Vapour pressure
- 0.21 ㎜Hg (25)
- Relative density
- 0.96 (25)
- n-Octanol/water partition coefficient (Kow)
- 4.330
- Molecular weight
- 258.4
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 23 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Plasticizer12
- Softener and conditioner5
- Processing aids not otherwise specified2
- Film former2
- Solvent2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 2 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 6 studies
- Classification not possible
Skin Irritation · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) ( adopted 12 May 1981) - Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) (adopted 12 May 1981) according to - Classification not possible
Skin Sensitization · Screening - Classification not possible
Eye Irritation · Screening - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) ( adopted 12 May 1981) according to
Source: US EPA CompTox dashboard
Related literature
- Effect of emollients on UV filter absorbance and sunscreen efficiency. · 2020
- Amended Final Report of the Safety Assessment of Dibutyl Adipate as Used in Cosmetics1 · 2006
- Final Report on the Safety Assessment of Stearamide DIBA-Stearate · 2001
- Final Report on the Safety Assessment of Dibutyl Adipate · 1996
- The effect of the vehicle formulation on the stratum corneum penetration characteristics of clobetasol 17‐propionate in vivo · 1988
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3 4
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata