Ingredient Dictionary

DIETHANOLAMINE

Diethanolamine can cause cancer according to California Labor Code.

Definition

Diethanolamine can cause cancer according to California Labor Code.

Source: PubChem

US FDA substance register · UNII AZE05TDV2V · registered name Diethanolamine · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps pH steadyBUFFERING

Safety & regulatory references

Banned: Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics

Source: Health Canada Cosmetic Ingredient Hotlist

Restriction II/411

Source: EU CosIng ingredient list

Reviewed by CIR: Final Report on the Safety Assessment of Triethanolamine, Diethanolamine, and Monoethanolamine

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Safety Assessment of Diethanolamine and Its Salts as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ＤＥＡ: 本品は、次の化学式で表されるアルカノールアミンである。

Source: JCIA labelling names (Japan)

Names & identifiers

DIETHANOLAMINEINCI다이에탄올아민Korean label name (MFDS standard)Ethanol, 2,2'-iminobis-SynonymＤＥＡJapanese labelling name

CAS No.chemical registry number: 111-42-2
EC No.EU chemical inventory number: 203-868-0
DTXSIDUS EPA chemical ID: DTXSID3021932
DTXCIDUS EPA compound ID: DTXCID601932

IUPAC: 2,2'-Azanediyldi(ethan-1-ol)
Molecular formula: C4H11NO2
Molecular weight: 105.137 g/mol

Measured properties

Appearance: Diethanolamine appears as oily colorless liquid or solid white crystals. Slight rotten fish or ammonia odor. Denser than water. (USCG, 1999) · Large Crystals, CBI, Liquid
Odour: Mild, ammonia-like odor
Boiling point: 516.4 °F at 760 mmHg (Decomposes) (NTP, 1992) · 268.8 °C
Melting point: 82 °F (NTP, 1992) · 27.9 °C
Solubility: greater than or equal to 100 mg/mL at 57 °F (NTP, 1992) · Miscible (1X10+6 mg/L) with water at 20 °C
Density: 1.095 at 82.4 °F (USCG, 1999) - Denser than water, will sink · 1.0966 at 20 °C
Viscosity: 351.9 cP at 30 °C, 53.85 cP at 60 °C · 351.9 (30℃)
pH: 11
Melting/freezing point: 28 ℃
Initial boiling point and range: 269 ℃
Flash point: 134 ℃
Upper/lower flammability or explosive limits: 9.8 / 1.7 %
Vapour pressure: (&amp, lt, 1 Pa, 20℃)
Vapour density: 3.65
Relative density: 1.09
n-Octanol/water partition coefficient (Kow): -1.43
Auto-ignition temperature: 662 ℃
Molecular weight: 105.135

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 136 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Chelating agent73
Degradant/impurity (EPA)17
pH regulating agent5
Surface modifier5
Corrosion inhibitor4
Surfactant (surface active agent)3
Intermediate3
Waterproofing agent3

17 other uses

Solids separation (precipitating) agent, not other2
Chemical reaction regulator2
Humectant2
Plasticizer2
Pigment2
Solvent2
Processing aids not otherwise specified1
Tanning agents not otherwise specified1
Catalyst1
Solubility enhancer1
Monomers1
Cleaning agent1
Stabilizing agent1
Emulsifier1
Hydraulic fluids1
Soil amendments1
Fragrance1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

8 skin studies and 5 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 13 studies

Category 2
Skin Irritation · Screening
Category 6.3B (Category 3)
Skin Irritation · Read Across
Category 6.3A (Category 2)
Skin Irritation · Read Across
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Not classified
Skin Sensitization · Screening
Skin Irrit. 2
Skin Irritation · Authoritative
Skin corrosion/irritation - Category 2
Skin Irritation · Screening
Sh
Skin Sensitization · Authoritative
Category 8.3A (Category 1)
Eye Irritation · Read Across
Serious eye damage/eye irritation - Category 2A
Eye Irritation · Screening
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Eye Dam. 1
Eye Irritation · Authoritative
Category 1
Eye Irritation · Screening