2-diethylaminoethanol is a member of the class of ethanolamines that is aminoethanol in which the hydrogens of the amino group are replaced by ethyl groups.
Definition
2-diethylaminoethanol is a member of the class of ethanolamines that is aminoethanol in which the hydrogens of the amino group are replaced by ethyl groups. It is a primary alcohol, a member of ethanolamines and a tertiary amino compound. It is functionally related to an ethanolamine. It derives from a hydride of a triethylamine.
Source: PubChem
US FDA substance register · UNII S6DL4M053U · registered name 2-(Diethylamino)ethanol · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ジエチルエタノールアミン: 本品は、次の化学式で表されるアミン誘導体である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 100-37-8
- EC No.EU chemical inventory number
- 202-845-2
- DTXSIDUS EPA chemical ID
- DTXSID5021837
- DTXCIDUS EPA compound ID
- DTXCID401837
- IUPAC
- 2-(Diethylamino)ethan-1-ol
- Molecular formula
- C6H15NO
- Molecular weight
- 117.192 g/mol
Measured properties
- Appearance
- 2-diethylaminoethanol appears as a colorless liquid. Flash point 103-140 °F. Less dense than water. Vapors heavier than air. Produces toxic oxides of nitrogen during combustion. Causes burns to the skin, eyes and mucous membranes. · Liquid
- Odour
- NAUSEATING ODOR · Nauseating, ammonia-like odor.
- Boiling point
- 325 °F at 760 mmHg (NTP, 1992) · 163 °C @ 760 MM HG
- Melting point
- -94 °F (NTP, 1992) · FREEZING POINT: -70 °C
- Solubility
- Very soluble (NTP, 1992) · SOL IN ALL PROPORTIONS IN WATER, SOL IN ALC, ETHER, ACETONE, BENZENE, PETROLEUM ETHER
- Density
- 0.8921 at 77 °F (USCG, 1999) - Less dense than water, will float · 0.8921 @ 20 °C/4 °C
- Stability
- Stability During Transport: Stable.
- Viscosity
- 5 mPa-s at 20 °C · (20℃)
- Dissociation constant
- pKa = 9.87 at 20 °C (conjugate acid)
- Colour
- colourless
- Melting/freezing point
- -70 ℃
- Initial boiling point and range
- 163 ℃
- Flash point
- 51.7 ℃
- Upper/lower flammability or explosive limits
- 28 / 1.9 %
- Vapour pressure
- 21 ㎜Hg (20℃)
- Vapour density
- 4.03
- Relative density
- 0.89 (20℃)
- n-Octanol/water partition coefficient (Kow)
- 0.46
- Auto-ignition temperature
- 250 ℃
- Molecular weight
- 117.19
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 7 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Processing aids not otherwise specified4
- pH regulating agent1
- Intermediate1
- Dispersing agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
7 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 9 studies
- Not classified
Skin Sensitization · Screening - Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Skin corrosion/irritation - Category 1
Skin Irritation · Screening - Skin Corr. 1B
Skin Irritation · Authoritative - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) - Category 1
Skin Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across - Category 1
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese