What is this ingredient?

미국 FDA 물질 등록 · UNII 860M3ZWF6J · 등록명 Diethyl Oxalate · 단일 화학물질

All ingredients

Ingredient Dictionary

DIETHYL OXALATE

Korean limit: 5%

Definition

US FDA substance register · UNII 860M3ZWF6J · registered name Diethyl Oxalate · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Listed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCEBase that dissolves other ingredientsSOLVENTKeeps a film flexiblePLASTICISERSoftens hairHAIR CONDITIONINGBinds metal ions to prevent spoilageCHELATING

Safety & regulatory references

Restricted: China · South Korea

Source: MFDS (Korea) cosmetic regulatory information

Argentina · Brazil

Field of application and/or use : Professional products for hair treatment
Maximum concentration permitted at final product : 5%
Use conditions and warnings that must appear on the label : For Professional use only

ASEAN

Field of application and/or use : Hair care products
Maximum authorised concentration in the finished cosmetic product : 5%
Conditions of use and warning which must be printed on the labels : For professional use only

European Union

Product Type, body parts : Hair products
Maximum concentration in ready for use preparation : 5%
Other : Professional use
Wording of conditions of use and warnings : For professional use only

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Restriction III/3

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name シュウ酸ジエチル: 本品は、シュウ酸（＊）とエタノールのジエステルであり、以下の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

DIETHYL OXALATEINCI다이에틸옥살레이트Korean label name (MFDS standard)Ethanedioic acid, diethyl esterSynonymシュウ酸ジエチルJapanese labelling name

CAS No.chemical registry number: 95-92-1
EC No.EU chemical inventory number: 202-464-1
DTXSIDUS EPA chemical ID: DTXSID2044472
DTXCIDUS EPA compound ID: DTXCID0024472

IUPAC: Diethyl ethanedioate
Molecular formula: C6H10O4
Molecular weight: 146.142 g/mol

Measured properties

Appearance: Ethyl oxalate appears as a colorless liquid. Slightly denser than water and insoluble in water. Hence sinks in water. May irritate skin and mucous membranes, may be mildly toxic by ingestion, may emit irritating fumes in a fire. Vapors are much heavier than air. Used as a solvent for plastics and in the manufacture of perfumes and pharmaceuticals. · Liquid
Odour: AROMATIC ODOR
Boiling point: 185.7 °C @ 760 MM HG · 185.4 °C @760 [mm Hg]
Melting point: -38.5 °C · -40.6 °C
Solubility: SPARINGLY SOL IN WATER WHICH DECOMP IT GRADUALLY, MISCIBLE WITH USUAL ORG SOLVENTS · SOL IN ALL PROPORTIONS IN ALCOHOL, ETHER, ACETONE
Density: 1.0785 @ 20 °C/4 °C · 1.079 @ 20°C
Stability: UNSTABLE
Colour: colourless
Melting/freezing point: -40.6 ℃
Initial boiling point and range: 185.7 ℃
Flash point: 75 ℃
Vapour pressure: 0.4132 ㎜Hg
Water solubility: 26200 ㎎/ℓ
Vapour density: 5.04
Relative density: 1.0785
n-Octanol/water partition coefficient (Kow): 0.56
Auto-ignition temperature: 410 ℃
Molecular weight: 146.14

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 11 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Intermediate2
Solvent2
Deodorizer1
Plasticizer1
Flavouring and nutrient1
Chelating agent1
Softener and conditioner1
Soil amendments1

1 other uses

Processing aids not otherwise specified1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 3 eye studies are on record.

Classed as moderate1Classed as low1

The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 7 studies

Skin corrosion - category 1B
Skin Irritation · Screening
Category 2
Skin Irritation · Screening
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay)
Classification not possible
Skin Sensitization · Screening
Eye Irrit. 2
Eye Irritation · Authoritative
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Classification not possible
Eye Irritation · Screening