Ingredient Dictionary

DIETHYLAMINE

Diethylamine is a secondary aliphatic amine where both N-substituents are ethyl.

Definition

Diethylamine is a secondary aliphatic amine where both N-substituents are ethyl. It is a conjugate base of a diethylammonium.

Source: PubChem

US FDA substance register · UNII B035PIS86W · registered name Diethylamine · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMINGListed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCEKeeps pH steadyBUFFERING

Safety & regulatory references

Banned: China · South Korea

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Restriction II/411 · Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

DIETHYLAMINEINCI다이에틸아민Korean label name (MFDS standard)Ethanamine, N-ethyl-Synonym

CAS No.chemical registry number: 109-89-7
EC No.EU chemical inventory number: 203-716-3
DTXSIDUS EPA chemical ID: DTXSID6021909
DTXCIDUS EPA compound ID: DTXCID501909

IUPAC: N-Ethylethanamine
Molecular formula: C4H11N
Molecular weight: 73.139 g/mol

Measured properties

Appearance: Diethylamine appears as a clear colorless liquid with an ammonia-like odor. Density 5.9 lb / gal. Flash point -15 °F. A respiratory irritant. Corrosive to the eyes and skin. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion. · Liquid
Odour: Fishy, ammonia-like odor
Boiling point: 131.9 °F at 760 mmHg (NTP, 1992) · 55.5 °C
Melting point: -58 °F (NTP, 1992) · -50 °C
Solubility: greater than or equal to 100 mg/mL at 63 °F (NTP, 1992) · In water, infinitely soluble /1X10+6 mg/L/ at 25 °C
Density: 0.708 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.7056 g/cu cm at 20 °C
Stability: Stable under recommended storage conditions.
Colour: colourless
Odour threshold: 0.14 ppm
Melting/freezing point: -50 ℃
Initial boiling point and range: 55.5 ℃(at 101.325Pa)
Flash point: -26 ℃
Evaporation rate: 16.9
Upper/lower flammability or explosive limits: 10.1 / 1.8 %
Vapour pressure: 25.9 ㎪ (20℃)
Water solubility: 100 g/100㎖ (25℃)
Vapour density: 2.5
Relative density: 0.7
n-Octanol/water partition coefficient (Kow): 0.58
Auto-ignition temperature: 312 ℃
Viscosity: 0.571 (25℃)
Molecular weight: 73.14

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 8 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Intermediate2
Catalyst1
Monomers1
Flavouring and nutrient1
pH regulating agent1
Fragrance1
Deodorizer1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

9 skin studies and 3 eye studies are on record.

Classed as highly irritating1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 12 studies

Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Category 8.2B (Category 1B)
Skin Irritation · Read Across
Category 6.5B (Category 1)
Skin Sensitization · Read Across
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to other guideline: Gad, S.C., Toxicol. Appl. Pharmacol., 1984, 93 - 114
Category 1
Skin Irritation · Screening
Skin Corr. 1A
Skin Irritation · Authoritative
Classification not possible
Skin Sensitization · Screening
Ambiguous
skin sensitisation: in vivo (LLNA) · Screening · equivalent or similar to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
Skin corrosion/irritation - Category 1
Skin Irritation · Screening
Category 1
Eye Irritation · Screening
Category 8.3A (Category 1)
Eye Irritation · Read Across
Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to