Coumarin 460 is a member of 7-aminocoumarins.
Definition
Coumarin 460 is a member of 7-aminocoumarins. It has a role as a fluorochrome.
Source: PubChem
US FDA substance register · UNII 1SFJ7F6R2C · registered name DIETHYLAMINOMETHYLCOUMARIN · single chemical substance
Cosmetic roles
Safety & regulatory references
- Allowed colourant
- United States
Source: US FDA prohibited and restricted ingredients
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ジエチルアミノメチルクマリン: 本品は、次の化学式で表される芳香族アミンである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 91-44-1
- EC No.EU chemical inventory number
- 202-068-9
- DTXSIDUS EPA chemical ID
- DTXSID9025035
- DTXCIDUS EPA compound ID
- DTXCID405035
- IUPAC
- 7-(Diethylamino)-4-methyl-2H-1-benzopyran-2-one
- Molecular formula
- C14H17NO2
- Molecular weight
- 231.295 g/mol
Measured properties
- Appearance
- solid
- Melting/freezing point
- 89 ℃
- Initial boiling point and range
- 240~243 ℃
- Vapour density
- 8.0
- n-Octanol/water partition coefficient (Kow)
- 3.22
- Auto-ignition temperature
- 430 ℃
- Molecular weight
- 231.30
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 8 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Brightener4
- Stabilizing agent2
- Dye2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: As given below - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: As mentioned below according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: as mentioned below according to
Source: US EPA CompTox dashboard
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA prohibited and restricted ingredients
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata