Diethylene glycol is a hydroxyether.
How much products actually contain
No product states its amount yet.
Of the products containing it, 0 list it before the 1% line and 1 after it (usually 1% or less).
Products using this ingredient
1 of 1 confirmed · likeliest to carry enough first
Definition
Diethylene glycol is a hydroxyether.
Source: PubChem
US FDA substance register · UNII 61BR964293 · registered name Diethylene Glycol · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- Argentina · ASEAN · Brazil · China · European Union · South Korea · Taiwan · United Kingdom
- Restricted or banned
- Argentina · ASEAN · Brazil · China · European Union · Japan · South Korea · Taiwan
- Restricted
- European Union · Japan · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS) · Health Canada Cosmetic Ingredient Hotlist · Japan Standards for Cosmetics
Canada
- Conditions of Use by product type : Not permitted in oral or leave-on products (see also "Glycerin").
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
EU Cosmetics Regulation, Annex III (restricted substances), entry 186 · maximum concentration 0.1% · applies to As traces in ingredients
EU Cosmetics Regulation, Annex II (prohibited substances), entry 1370
Restriction II/1370 III/186 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ジエチレングリコール: 本品は、グリコール(*)の2量体である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 111-46-6
- EC No.EU chemical inventory number
- 203-872-2
- DTXSIDUS EPA chemical ID
- DTXSID8020462
- DTXCIDUS EPA compound ID
- DTXCID20462
- IUPAC
- 2,2'-Oxydi(ethan-1-ol)
- Molecular formula
- C4H10O3
- Molecular weight
- 106.121 g/mol
Measured properties
- Colour
- colourless
- Odour
- odourless
- Melting/freezing point
- -6.5 ℃
- Initial boiling point and range
- 244~245 ℃
- Flash point
- 124 ℃(c.c.)
- Evaporation rate
- (&, lt, 0.001)
- Upper/lower flammability or explosive limits
- 12.2 / 1.8 %
- Vapour pressure
- 0.0057 ㎜Hg (25℃)
- Water solubility
- 100 g/100㎖ (25℃)
- Vapour density
- 3.66
- Relative density
- 1.1197 (15℃)
- n-Octanol/water partition coefficient (Kow)
- -1.47 (est.)
- Auto-ignition temperature
- 229 ℃
- Viscosity
- 30 cP (25℃)
- Molecular weight
- 106.12
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 151 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Processing aids not otherwise specified76
- Solvent14
- Binder13
- Monomers10
- Emulsifier4
- Deodorizer3
- Intermediate3
- Plasticizer3
18 other uses
- Surfactant (surface active agent)3
- Stabilizing agent2
- Lubricating agent2
- Fuel2
- No specific technical function2
- Fragrance2
- Anti-freeze agent1
- Soil amendments1
- Photosensitive agent1
- Propellants, non-motive (blowing agents)1
- Heat transferring agent1
- Tanning agents not otherwise specified1
- Chemical reaction regulator1
- Insulators1
- Thickening agent1
- Elasticizer1
- Viscosity modifier1
- Catalyst1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Not classified
Skin Sensitization · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to EU Method B.6 (Skin Sensitisation) - Not classified
Skin Irritation · Screening - Not classified
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Diethylene glycol poisoning from transcutaneous absorption: Case report · 2024
- THE TERATOGENIC EFFECT OF DIETHYLENE GLYCOL (DEG) ON FETUS MORPHOLOGY IN WHITE MICE (MUS MUSCULUS L.) · 2024
- Challenges in utilizing diethylene glycol and ethylene glycol as excipient: A thorough overview · 2023
- Review of Pharmaceutical Applications of Diethylene Glycol Monoethyl Ether. · 2022
- Diethylene glycol monoethyl ether: an emerging solvent in topical dermatology products · 2011
Linked databases 30
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- EU restricted substances (Annex III)
- EU SCCS safety opinions
- Health Canada Cosmetic Ingredient Hotlist
- Japan Standards for Cosmetics
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3 4
- NIST Chemistry WebBook
- PubChem
- Taiwan FDA cosmetic ingredients
- Tlooto literature search 2 3 4 5
- UK cosmetics regulations (OPSS) 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese