DIHYDROXYACETONE

Dihydroxyacetone is a ketotriose consisting of acetone bearing hydroxy substituents at positions 1 and 3. The simplest member of the class of ketoses and the parent of the class of glycerones. It has a role as a metabolite, an antifungal agent, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a primary alpha-hydroxy ketone and a ketotriose.

Source: PubChem

US FDA substance register · UNII O10DDW6JOO · registered name Dihydroxyacetone · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Dihydroxyacetone is the aliphatic ketone that conforms to the formula:

Restricted

South Korea · Taiwan

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic regulations

ASEAN

• Field of application and/or use : (a) Hair dye substance in non- oxidative hair dye products (b) Self-tanning products Use for dyeing eyelashes and eyebrows is not permitted.
• Maximum authorised concentration in the finished cosmetic product : (a) 6.25% (b) 10%

United States

• Eye Area : No
• Generally (Includes Lipsticks) : No
• External Use : Subject to limitations
• Specific Limitations and Comments : intended solely or in part to impart a color to the human body

European Union

• Product Type, body parts : (a) Hair dye substance in non-oxidative hair dye products (*) (b) Self-tanning products (*) (*) From 26 January 2022 hair dye and self-tanning products containing that substance and not complying with the restrictions shall not be placed on the Union market. From 22 April 2022 hair dye and self-tanning products containing that substance and not complying with the restrictions shall not be made available on the Union market
• Maximum concentration in ready for use preparation : (a) 6,25 % (b) 10 %

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex III (restricted substances), entry 322 · maximum concentration (a) 6,25 % (b) 10 % · applies to (a) Hair dye substance in non-oxidative hair dye products (*) (b) Self-tanning products (*) (*) From 26 January 2022 hair dye and self-tanning products containing that substance and not complying with the restrictions shall not be placed on the Union market. From 22 April 2022 hair dye and self-tanning products containing that substance and not complying with the restrictions shall not be made available on the Union market

Source: EU restricted substances (Annex III)

Restriction III/322 · Other restriction: ban substances that deplete the ozone layer · SCCS opinion: OPINION ON Dihydroxyacetone -DHA (1,3-Dihydroxy-2-propanone) CAS No. 96-26-4; Opinion on Dihydroxyacetone (DHA)

Source: EU CosIng ingredient list