Didodecyl thiobispropanoate is a dicarboxylic acid.
How much products actually contain
No product states its amount yet.
Of the products containing it, 2 list it before the 1% line and 12 after it (usually 1% or less).
Products using this ingredient
12 of 14 confirmed · likeliest to carry enough first · See all 14
ORLYORLY Harry Potter™ Dark Arts Crackle Topper
rhoderhode peptide glazing fluid
HourglassHourglass Equilibrium Resurfacing Retinoid Treatment
NeutrogenaNorwegian Formula Intense Repair Foot Cream 56g
NeutrogenaNorwegian Formula Foot Cream 56g, 2-Pack
FentyFenty Big Dripp'r Body Wash — Hey, Bouquet
FentyFenty Big Dripp'r Body Wash — Vanilla Flowers
numbuzinNo.5 Glutathione C Dark Spot Toning Laser Cream
numbuzinnumbuzin No.5 Glutathione C Dark Spot Toning Laser Cream
FATIONNOSCA9 Trouble Pore Firming Cream 45ml
FATIONNOSCA9 Trouble Pore Firming Cream 45ml
FATIONFATION NOSCA9 Trouble Pore Firming Cream 5ml (Trial Size)
Definition
Didodecyl thiobispropanoate is a dicarboxylic acid.
Source: PubChem
US FDA substance register · UNII V51YH1B080 · registered name DILAURYL THIODIPROPIONATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Final Safety Assessment of Thiodipropionic Acid and its Dialkyl Esters as Used in Cosmetics
Reviewed by CIR: Final Report on the Safety Assessment of Dilauryl Thiodipropionate
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name チオジプロピオン酸ジラウリル: 本品は、３，３’－チオジプロピオン酸とラウリルアルコール（＊）のジエステルであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 123-28-4
- EC No.EU chemical inventory number
- 204-614-1
- DTXSIDUS EPA chemical ID
- DTXSID2026999
- DTXCIDUS EPA compound ID
- DTXCID706999
- IUPAC
- Didodecyl 3,3'-sulfanediyldipropanoate
- Molecular formula
- C30H58O4S
- Molecular weight
- 514.85 g/mol
Measured properties
- Appearance
- CBI, Large Crystals, Dry Powder, Liquid, Other Solid · White solid with a sweet odor, [Hawley] White crystalline powder, [MSDSonline]
- Odour
- Sweetish odor
- Melting point
- 40 °C · 43 - 44 °C
- Solubility
- Soluble in most organic solvents
- Density
- 0.975 at 25 °C (solid 25 °C)
- Melting/freezing point
- 38~40 ℃
- Flash point
- 219 ℃
- Flammability (solid, gas)
- not flammable
- Vapour pressure
- 0 ㎩ (20℃)
- Water solubility
- &, lt, 1 ㎎/ℓ (20℃)
- Vapour density
- 1040 ㎏/㎥ (20℃)
- Relative density
- 0.975
- n-Octanol/water partition coefficient (Kow)
- 11.79 (25℃)
- Decomposition temperature
- &, gt, 275 ℃ (1013 hPa)
- Molecular weight
- 514.94
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 42 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Antioxidant16
- Preservative8
- Processing aids not otherwise specified4
- Fragrance3
- UV stabilizer3
- pH regulating agent2
- Heat stabilizer2
- Filler1
3 other uses
- Chemical reaction regulator1
- Plasticizer1
- Intermediate1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 5 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to other guideline: "Appraisal of the Safety of Chemicals in Foods, Drugs and Cosmetics" (1959), of the US Association of Food and Drug Officials (AFDO) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to other guideline: "Hazardous Substances Regulations" under the U.S. Federal Hazardous Substances Labelling Act Sect. 191.11 (February 1965) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to other guideline: "Hazardous Substances Regulations" U.S.A. Federal Hazardous Substances Labelling Act Sect. 191.12 (February 1965), with slight modification. according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
- Chemical Composition, Antioxidant Potential, and Antimicrobial Activity of Novel Antiseptic Lotion from the Leaves of Betula pendula Roth · 2025
- Final Safety Assessment of Thiodipropionic Acid and Its Dialkyl Esters as Used in Cosmetics · 2010
- 2 Final Report on the Safety Assessment of Dilauryl Thiodipropionate · 1992
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata