Ingredient Dictionary

DIMETHYL ADIPATE

Dimethyl adipate is a fatty acid methyl ester.

Definition

Dimethyl adipate is a fatty acid methyl ester.

Source: PubChem

US FDA substance register · UNII BY71RX0R62 · registered name DIMETHYL ADIPATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Base that dissolves other ingredientsSOLVENTMakes skin soft and smoothSKIN CONDITIONING - EMOLLIENTKeeps a film flexiblePLASTICISER

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Final Report of the Cosmetic Ingredient Review Expert Panel on the Safety Assessment of Dicarboxylic Acids, Salts and Esters

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name アジピン酸ジメチル: 本品は、アジピン酸（＊）とメチルアルコールのジエステルであり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

DIMETHYL ADIPATEINCI다이메틸아디페이트Korean label name (MFDS standard)Hexanedioic acid, dimethyl esterSynonymアジピン酸ジメチルJapanese labelling name

CAS No.chemical registry number: 627-93-0
EC No.EU chemical inventory number: 211-020-6
DTXSIDUS EPA chemical ID: DTXSID8025096
DTXCIDUS EPA compound ID: DTXCID605096

IUPAC: Dimethyl hexanedioate
Molecular formula: C8H14O4
Molecular weight: 174.196 g/mol

Measured properties

Appearance: liquid
Colour: colourless
Melting/freezing point: 10.3 ℃
Initial boiling point and range: 230.9 ℃
Flash point: 116 ℃(c.c.)
Flammability (solid, gas): flammable
Upper/lower flammability or explosive limits: 8.1 / 0.81 %
Vapour pressure: 23 ㎩ (at 20 ℃)
Water solubility: 6000 ㎎/ℓ (at 0 ℃)
Vapour density: 6.01
Relative density: 1.06 (at 20 ℃ / 4 ℃)
n-Octanol/water partition coefficient (Kow): 1.03
Auto-ignition temperature: 400 ℃
Viscosity: (3 mPa s at 20 ℃)
Molecular weight: 174.20

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 138 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance91
Solvent21
Softener and conditioner6
Processing aids not otherwise specified4
Plasticizer3
Dispersing agent2
Cleaning agent2
Thickening agent2

7 other uses

Intermediate1
Monomers1
Solubility enhancer1
Flavouring and nutrient1
Lubricating agent1
Viscosity modifier1
Surface modifier1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Department of Transportation, Hazardous Materials Regulations, title 49 CFR, Section 173.240(a)(1), December 31, 1973 according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EPA OTS 798.4470 (Acute Dermal Irritation) according to
Moderate or Mild Irritation
eye irritation: in vivo · Screening · EPA OTS 798.4500 (Acute Eye Irritation) according to