この成分は何ですか?

이 원료는 다음의 구조를 갖는 유기화합물이다.

成分一覧

成分辞典

DIMETHYL ITACONATE

定義

米国FDA 物質登録 · UNII 11JIB0YI93 · 登録名 DIMETHYL ITACONATE · 単一の化学物質

出典: 米国FDA 物質識別番号（UNII）

Dimethyl Itaconate is the organic compound that conforms to the formula

化粧品での役割

酸素による劣化を遅らせるANTIOXIDANT上記に属さない肌コンディショニングSKIN CONDITIONING - MISCELLANEOUS外部刺激から肌を守るSKIN PROTECTING髪をやわらかくするHAIR CONDITIONING

安全性・規制情報

韓国の有害物質GHS分類なし · 既存化学物質

出典: 韓国有害物質GHS情報（環境公団）

詳しい資料 — 表示名・識別番号・物性・試験記録・文献

別名・識別情報

DIMETHYL ITACONATEINCI다이메틸이타코네이트韓国の表示名（食薬処標準名）

CAS No.化学物質登録番号: 617-52-7
EC No.EU化学物質目録番号: 210-519-6
DTXSID米国EPA化学物質番号: DTXSID80210701
DTXCID米国EPA化合物番号: DTXCID70133192

IUPAC: Dimethyl 2-methylidenebutanedioate
分子式: C7H10O4
分子量: 158.153 g/mol

測定された物性

融点・凝固点: 38 ℃(EXP)
初留点および沸点範囲: 208 ℃(EXP)
引火点: 100 ℃(c.c)
溶解度: 14030 ㎎/ℓ
比重: 1.1241 ( at 18℃)
n-オクタノール/水分配係数（Kow）: 0.820 (推定値)
分子量: 158.152

物質そのものを測定した値です。安全保健公団（KOSHA）の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。

出典: 韓国安全保健公団 SDS

刺激・感作試験の記録

皮膚試験5件・眼試験4件の記録があります。

刺激が強いと分類3件中程度と分類1件

試験の結論はおおむね一致しています（75%）。原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。

試験9件をすべて見る

Severe Irritation
skin corrosion: in vitro / ex vivo · Screening · OECD Guideline 439 (In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method) adopted 22 July 2010 according to EU Method B.46 (In Vitro Skin Irritation: Reconstructed Human Epidermis Model Test) according to
Corrosive
skin corrosion: in vitro / ex vivo · Screening · EU Method B.46 (In Vitro Skin Irritation: Reconstructed Human Epidermis Model Test) Official Journal of the European Union No. L142; Amended by EC No. 640/2012 OJ No. L193, 20 July 2012 ( (EpiSkin model)) according to OECD Guideline 439 (In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method) adopted 26 July 2013 (EpiSkin model) according to
SkinSens1
Skin Sensitization · QSAR Predicted
High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) as at 2002 according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) as at 2008 according to EPA OPPTS 870.2600 (Skin Sensitisation) as at 2003
Low to Moderate Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay)
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: FAMIC according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to EPA OPPTS 870.2400 (Acute Eye Irritation) according to
Corrosive or Irritation Persists for > 21 days
eye irritation: in vitro / ex vivo · Screening · OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants) [before 26 July 2013] according to EU method B.47 (Bovine corneal opacity and permeability test method for identifying ocular corrosives and severe irritants) according to
Corrosive or Irritation Persists for > 21 days
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline no. 437: "Bovine corneal opacity and permeability (BCOP) test method for identifying ocular corrosives and severe irritants" (adopted September 07, 2009) according to
Moderate or Mild Irritation
eye irritation: in vitro / ex vivo · Screening · OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants) [before 26 July 2013] according to EU method B.47 (Bovine corneal opacity and permeability test method for identifying ocular corrosives and severe irritants) according to

出典: 米国EPA CompTox