这种成分是什么?

이 원료는 다음의 구조를 갖는 유기화합물이다.

成分列表

成分词典

DIMETHYL ITACONATE

定义

美国FDA 物质登记 · UNII 11JIB0YI93 · 登记名称 DIMETHYL ITACONATE · 单一化学物质

来源: 美国FDA 物质识别码（UNII）

Dimethyl Itaconate is the organic compound that conforms to the formula

化妆品中的作用

延缓产品因氧化变质ANTIOXIDANT不属于以上类别的皮肤调理SKIN CONDITIONING - MISCELLANEOUS保护肌肤免受外界刺激SKIN PROTECTING柔顺头发HAIR CONDITIONING

安全与法规参考

未列入韩国有毒物质 GHS 分类 · 现有化学物质

来源: 韩国有毒物质 GHS 信息（环境公团）

详细资料——标示名称、识别编号、物性、试验记录、文献

别名和识别信息

DIMETHYL ITACONATEINCI다이메틸이타코네이트韩国标示名称（食药处标准名）

CAS No.化学物质登记号: 617-52-7
EC No.欧盟化学品目录编号: 210-519-6
DTXSID美国EPA化学品编号: DTXSID80210701
DTXCID美国EPA化合物编号: DTXCID70133192

IUPAC: Dimethyl 2-methylidenebutanedioate
分子式: C7H10O4
分子量: 158.153 g/mol

实测物性

熔点/凝固点: 38 ℃(EXP)
初沸点和沸程: 208 ℃(EXP)
闪点: 100 ℃(c.c)
溶解度: 14030 ㎎/ℓ
比重: 1.1241 ( at 18℃)
正辛醇/水分配系数（Kow）: 0.820 (估算值)
分子量: 158.152

这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。

来源: 韩国安全保健公团安全数据表

刺激与致敏试验记录

记录有皮肤试验 5 项、眼部试验 4 项。

归类为刺激性高3 项归类为中等1 项

试验结论基本一致（75%）。这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。

查看全部 9 项试验

Severe Irritation
skin corrosion: in vitro / ex vivo · Screening · OECD Guideline 439 (In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method) adopted 22 July 2010 according to EU Method B.46 (In Vitro Skin Irritation: Reconstructed Human Epidermis Model Test) according to
Corrosive
skin corrosion: in vitro / ex vivo · Screening · EU Method B.46 (In Vitro Skin Irritation: Reconstructed Human Epidermis Model Test) Official Journal of the European Union No. L142; Amended by EC No. 640/2012 OJ No. L193, 20 July 2012 ( (EpiSkin model)) according to OECD Guideline 439 (In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method) adopted 26 July 2013 (EpiSkin model) according to
SkinSens1
Skin Sensitization · QSAR Predicted
High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) as at 2002 according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) as at 2008 according to EPA OPPTS 870.2600 (Skin Sensitisation) as at 2003
Low to Moderate Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay)
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: FAMIC according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to EPA OPPTS 870.2400 (Acute Eye Irritation) according to
Corrosive or Irritation Persists for > 21 days
eye irritation: in vitro / ex vivo · Screening · OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants) [before 26 July 2013] according to EU method B.47 (Bovine corneal opacity and permeability test method for identifying ocular corrosives and severe irritants) according to
Corrosive or Irritation Persists for > 21 days
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline no. 437: "Bovine corneal opacity and permeability (BCOP) test method for identifying ocular corrosives and severe irritants" (adopted September 07, 2009) according to
Moderate or Mild Irritation
eye irritation: in vitro / ex vivo · Screening · OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants) [before 26 July 2013] according to EU method B.47 (Bovine corneal opacity and permeability test method for identifying ocular corrosives and severe irritants) according to

来源: 美国EPA CompTox