Cosmetic roles
Makes skin soft and smoothSKIN CONDITIONING - EMOLLIENTBase that dissolves other ingredientsSOLVENT
Safety & regulatory references
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
DIMETHYL MALEATEINCI다이메틸말리에이트Korean label name (MFDS standard)
- CAS No.chemical registry number
- 23055-10-9
- CAS No.chemical registry number
- 624-48-6
- CAS No.chemical registry number
- 624-48-6 / 23055-10-9
- EC No.EU chemical inventory number
- 210-848-5
- DTXSIDUS EPA chemical ID
- DTXSID4040765
- DTXCIDUS EPA compound ID
- DTXCID2020765
- IUPAC
- Dimethyl (2Z)-but-2-enedioate
- Molecular formula
- C6H8O4
- Molecular weight
- 144.126 g/mol
Measured properties
- Appearance
- Clear colorless liquid, [Sigma-Aldrich MSDS]
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent1
- Plasticizer1
- Softener and conditioner1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
7 skin studies and 3 eye studies are on record.
Classed as highly irritating2Classed as low4
The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 10 studies
- Category 1
Skin Sensitization · Screening - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - SkinSens1
Skin Sensitization · QSAR Predicted - Not classified
Skin Irritation · Screening - High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) - Category 2B
Eye Irritation · Screening - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Linked databases 14
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL 2
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- Wikidata
- Wikipedia · English · Japanese · Chinese