N,N-dimethylethanolamine is a tertiary amine that is ethanolamine having two N-methyl substituents.
Definition
N,N-dimethylethanolamine is a tertiary amine that is ethanolamine having two N-methyl substituents. It has a role as a radical scavenger and a curing agent. It is a member of ethanolamines and a tertiary amine.
Source: PubChem
US FDA substance register · UNII 2N6K9DRA24 · registered name Deanol · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Restriction III/62
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ジメチルＭＥＡ: 本品は、次の化学式で表されるアミノアルコールである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 108-01-0
- EC No.EU chemical inventory number
- 203-542-8
- DTXSIDUS EPA chemical ID
- DTXSID2020505
- DTXCIDUS EPA compound ID
- DTXCID00505
- IUPAC
- 2-(Dimethylamino)ethan-1-ol
- Molecular formula
- C4H11NO
- Molecular weight
- 89.138 g/mol
Measured properties
- Appearance
- 2-dimethylaminoethanol appears as a clear colorless liquid with a fishlike odor. Flash point 105 °F. Less dense than water. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion. Used to make other chemicals. · Liquid
- Odour
- Amine odor · Fishy odor
- Boiling point
- 275 °F at 758 mmHg (NTP, 1992) · 134.1 °C
- Melting point
- -74 °F (NTP, 1992) · -65 °C
- Solubility
- greater than or equal to 100 mg/mL at 73 °F (NTP, 1992) · Miscible with water
- Density
- 0.887 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.8866 g/cu cm at 20 °C
- Stability
- Stable under recommended storage conditions.
- Viscosity
- 3.5839 mPa.s at 21.6 °C · 3 cP (20℃)
- Dissociation constant
- 9 · pKa = 9.3
- Colour
- colourless
- Odour threshold
- 0.04 ppb
- pH
- 11-12
- Melting/freezing point
- -59 ℃
- Initial boiling point and range
- 134 ℃
- Flash point
- 38 ℃(c.c.)
- Evaporation rate
- 0.48
- Upper/lower flammability or explosive limits
- 11.9 / 1.6 %
- Vapour pressure
- 612 ㎩ (20℃)
- Water solubility
- 100 g/100㎖
- Vapour density
- 3.1
- Relative density
- 0.8866
- n-Octanol/water partition coefficient (Kow)
- -0.94 (est.)
- Auto-ignition temperature
- 220 ℃
- Molecular weight
- 89.14
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 38 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- pH regulating agent11
- Degradant/impurity (EPA)4
- Processing aids not otherwise specified4
- Catalyst4
- Preservative3
- Hydraulic fluids2
- Corrosion inhibitor2
- Chemical reaction regulator1
7 other uses
- Solvent1
- Waterproofing agent1
- Intermediate1
- Flame retardant1
- Monomers1
- Cleaning agent1
- Binder1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
10 skin studies and 5 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 15 studies
- Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to other guideline: Guinea-pig maximisation test - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: EPA 40 CFR Part 158 - Category 6.3A (Category 2)
Skin Irritation · Read Across - Skin corrosion/irritation - Category 1
Skin Irritation · Screening - Category 1
Skin Irritation · Screening - Category 1
Skin Sensitization · Screening - Skin Corr. 1B
Skin Irritation · Authoritative - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Category 8.3A (Category 1)
Eye Irritation · Read Across - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Category 1
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese