- Korean limit
- 2.5%
Definition
US FDA substance register · UNII 5E4O85D8T2 · registered name DIMETHYL MYRISTAMINE · single chemical substance
Cosmetic roles
Safety & regulatory references
- Restricted
- China · South Korea
Source: MFDS (Korea) cosmetic regulatory information
Argentina · Brazil
- Field of application and/or use : (a) Products without rinse. (b) Other products.
- Maximum concentration permitted at final product : (a) 2.5%
- Other limitations and requirements : a.- b.- . No use with nitrosating systems . -Pureza minimum 99% maximum -Tenor of secondary amines in raw materials 0.5%. Maximum nitrosamine -Tenor. 50 ug / kg -Envasar / keep in containers free of nitrites
ASEAN
- Field of application and/or use : (a) non-rinse-off products (b) other products
- Maximum authorised concentration in the finished cosmetic product : (a) 2.5%
- Other limitations and requirements : (a) (b): • Do not use with nitrosating systems • Minimum purity: 99% • Maximum secondary amine content: 0.5% (applies to raw materials) • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers
European Union
- Product Type, body parts : (a) Leave-on products (b) Rinse-off products
- Maximum concentration in ready for use preparation : (a) 2.5%
- Other : (a) (b) - Do not use with nitrosating systems - Minimum purity: 99% - Maximum secondary amine content: 0.5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Restriction III/62
Source: EU CosIng ingredient list
Reviewed by CIR: Final Amended Safety Assessment of the Cosmetic Ingredient Review Expert Panel: Dimethyl Stearamine and Related Tertiary Aliphatic Amines as Used in Cosmetics (Dimethyl Stearamine, Dimethyl Lauramine, Dimethyl Myristamine, Dimethyl Pamitamine, Dimethyl Behenamine, Dimethyl Cocamine, Dimethyl Tallowamine, Dimethyl Hydrogenated Tallowamine, Dimethyl Soyamine)
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 112-75-4
- EC No.EU chemical inventory number
- 204-002-4
- DTXSIDUS EPA chemical ID
- DTXSID4026927
- DTXCIDUS EPA compound ID
- DTXCID806927
- IUPAC
- N,N-Dimethyltetradecan-1-amine
- Molecular formula
- C16H35N
- Molecular weight
- 241.463 g/mol
Measured properties
- Appearance
- CBI, Liquid · Light yellow liquid with a fishy odor, [CAMEO] Colorless to yellow liquid, Clear or slightly cloudy with a fishy odor, [MSDSonline]
- Stability
- ACID-STABLE
- Colour
- colourless
- Melting/freezing point
- -21 ℃(1013 hPa)
- Initial boiling point and range
- 276 ℃
- Flash point
- 121 ℃
- Flammability (solid, gas)
- not flammable
- Vapour pressure
- 0.009 hPa (20℃)
- Water solubility
- 1.51 g/ℓ (21℃)
- Vapour density
- 0.791 g/㎤
- n-Octanol/water partition coefficient (Kow)
- 58.94 (Pow, 20℃)
- Auto-ignition temperature
- 235 ℃ (1006 hPa)
- Viscosity
- 3.39 mPa S
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 10 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Surfactant (surface active agent)4
- Intermediate2
- Corrosion inhibitor2
- Anti-static agent1
- Softener and conditioner1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 7 studies
- Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - SkinSens1
Skin Sensitization · QSAR Predicted - SkinIrr2
Skin Irritation · QSAR Predicted - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Linked databases 17
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata