Definition
US FDA substance register · UNII Y772Z5O19G · registered name DIMETHYLOL GLYCOL · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 3586-55-8
- EC No.EU chemical inventory number
- 222-720-6
- DTXSIDUS EPA chemical ID
- DTXSID5041225
- DTXCIDUS EPA compound ID
- DTXCID3021225
- IUPAC
- [Ethane-1,2-diylbis(oxy)]dimethanol
- Molecular formula
- C4H10O4
- Molecular weight
- 122.12 g/mol
Measured properties
- Appearance
- liquid
- Melting/freezing point
- 25.78 ℃
- Initial boiling point and range
- 89.6 ℃(760mmHg)
- Flash point
- 8 ℃
- Vapour pressure
- 0.00489 ㎜Hg
- Water solubility
- 100000 ㎎/ℓ
- Relative density
- 1.193
- n-Octanol/water partition coefficient (Kow)
- -2.73
- Molecular weight
- 122.12
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Biocide2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 3 eye studies are on record.
The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 7 studies
- Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EU Method B.6 (Skin Sensitisation) - Category 6.3A (Category 2)
Skin Irritation · Read Across - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) (Version Feb. 1987) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Linked databases 10
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata