Definition
US FDA substance register · UNII 8C3FKR6R1B · registered name 1,4-CYCLOHEXANEDIMETHANOL · mixture
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 105-08-8
- EC No.EU chemical inventory number
- 203-268-9
- DTXSIDUS EPA chemical ID
- DTXSID9026712
- DTXCIDUS EPA compound ID
- DTXCID106712
- IUPAC
- (Cyclohexane-1,4-diyl)dimethanol
- Molecular formula
- C8H16O2
- Molecular weight
- 144.214 g/mol
Measured properties
- Appearance
- solid
- Melting/freezing point
- 41~61 ℃
- Initial boiling point and range
- 283 ℃
- Flash point
- 161 ℃
- Vapour pressure
- 0.000308 ㎜Hg (at 25℃)
- Water solubility
- 4310 ㎎/ℓ
- Relative density
- 1.038 (at 25℃)
- n-Octanol/water partition coefficient (Kow)
- 1.49 ()
- Auto-ignition temperature
- 316 ℃
- Viscosity
- 675 cP (at 50℃)
- Molecular weight
- 144.21
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 8 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent2
- Monomers2
- No specific technical function2
- Processing aids not otherwise specified2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 4 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 6 studies
- SkinIrr2
Skin Irritation · QSAR Predicted - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EPA OPPTS 870.2500 (Acute Dermal Irritation) according to - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Eye damage - category 1
Eye Irritation · Screening - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Moderate or Mild Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EPA OPPTS 870.2400 (Acute Eye Irritation) according to
Source: US EPA CompTox dashboard
Linked databases 13
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese