Ingredient Dictionary

DIMETHYLTOLYLAMINE

N,N-Dimethyl-p-toluidine can cause cancer according to The National Toxicology Program.

Definition

N,N-Dimethyl-p-toluidine can cause cancer according to The National Toxicology Program.

Source: PubChem

US FDA substance register · UNII S8XC5939VU · registered name DIMETHYLTOLYLAMINE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Dimethyltolylamine is the organic compound that conforms to the formula

Cosmetic roles

Builds artificial nailsNAIL SCULPTING

Safety & regulatory references

Banned: European Union · United Kingdom

Source: EU Cosmetics Regulation · UK cosmetics regulations (OPSS)

Korea’s toxic-substance GHS classification: Danger · H301 (category 3) · H332 (category 4) · H350 (category 1B) · +2 more

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex II (prohibited substances), entry 1745

Source: EU prohibited substances (Annex II)

Restriction II / 1745

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ジメチルトリルアミン: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

DIMETHYLTOLYLAMINEINCI다이메틸톨릴아민Korean label name (MFDS standard)Benzenamine, N,N,4-trimethyl-SynonymジメチルトリルアミンJapanese labelling name

CAS No.chemical registry number: 99-97-8
EC No.EU chemical inventory number: 202-805-4
DTXSIDUS EPA chemical ID: DTXSID0021832
DTXCIDUS EPA compound ID: DTXCID401832

IUPAC: N,N,4-Trimethylaniline
Molecular formula: C9H13N
Molecular weight: 135.21 g/mol

Measured properties

Appearance: N,n-dimethyl-p-toluidine appears as a clear colorless liquid with an aromatic odor. Density 0.937 g / cm3 (Lancaster) and insoluble in water. Hence floats on water. Toxic by skin absorption and inhalation. May release toxic vapors when burned. · Liquid
Odour: Aromatic
Boiling point: 211 °C · 215 °C
Solubility: In water, 455 mg/L · In water, 650 mg/L at 37 °C
Density: 0.9366 g/cu cm at 20 °C · Relative density (water = 1): 0.9
Stability: Stable under recommended storage conditions.
Dissociation constant: pKa = 5.63 at 25 °C (conjugate acid)
Melting/freezing point: -15 ℃
Initial boiling point and range: 211 ℃
Flash point: 83 ℃
Upper/lower flammability or explosive limits: 7.0 / 1.2 %
Vapour pressure: 0.178 ㎜Hg (25 deg c)
Water solubility: 650 ㎎/ℓ (37 deg c)
Vapour density: 4.7 ((air=1))
Relative density: 0.940 (0.940~0.944(15/4 deg c)
n-Octanol/water partition coefficient (Kow): 2.81
Auto-ignition temperature: 425 ℃
Viscosity: 0.864 cP (55℃)
Molecular weight: 135.21

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 9 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Catalyst4
Processing aids not otherwise specified2
Softener and conditioner1
Intermediate1
Hardener1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

5 skin studies and 2 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 7 studies

Classification not possible
Skin Irritation · Screening
Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline:
Category 6.3B (Category 3)
Skin Irritation · Read Across
Classification not possible
Skin Sensitization · Screening
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Classification not possible
Eye Irritation · Screening