Ingredient Dictionary

DIOSGENIN

Diosgenin is a sapogenin that is spirostan which is substituted by a hydroxy group at the 3beta position, contains a double bond at the 5-6 position, and has R- configuration at position 25.

Definition

Diosgenin is a sapogenin that is spirostan which is substituted by a hydroxy group at the 3beta position, contains a double bond at the 5-6 position, and has R- configuration at position 25. A natural product found in Dioscorea (wild yam) species, it is used as the starting point for the commercial synthesis of a number of steroids, including cortisone, pregnenolone and progesterone. It has a role as an antiviral agent, a metabolite, an antineoplastic agent and an apoptosis inducer. It is a sapogenin, a 3beta-sterol, a hexacyclic triterpenoid and a spiroketal. It derives from a hydride of a spirostan.

Source: PubChem

US FDA substance register · UNII K49P2K8WLX · registered name DIOSGENIN · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps skin in good condition (CosIng catch-all)SKIN CONDITIONING

Safety & regulatory references

Restriction II/260

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ジオスゲニン: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

DIOSGENININCIジオスゲニンJapanese labelling name

CAS No.chemical registry number: 512-04-9
EC No.EU chemical inventory number: 208-134-3
DTXSIDUS EPA chemical ID: DTXSID00895074
DTXCIDUS EPA compound ID: DTXCID301324626

IUPAC: (25R)-Spirost-5-en-3beta-ol
Molecular formula: C27H42O3
Molecular weight: 414.63 g/mol

What products actually use it for

What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Softener and conditioner1

Source: US EPA CompTox dashboard