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Ingredient Dictionary

DIPALMITOYL HYDROXYPROLINE

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 24 list it before the 1% line and 10 after it (usually 1% or less).

Products using this ingredient

12 of 34 confirmed · likeliest to carry enough first · See all 34

Definition

US FDA substance register · UNII E6AHA53N1H · registered name DIPALMITOYL HYDROXYPROLINE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Softens hairHAIR CONDITIONINGKeeps skin in good condition (CosIng catch-all)SKIN CONDITIONINGReduces staticANTISTATIC
More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ジパルミトイルヒドロキシプロリン: 本品は、次の化学式で表されるプロリン誘導体である。

Source: JCIA labelling names (Japan)

Names & identifiers

DIPALMITOYL HYDROXYPROLINEINCI다이팔미토일하이드록시프롤린Korean label name (MFDS standard)ジパルミトイルヒドロキシプロリンJapanese labelling name
CAS No.chemical registry number
41672-81-5
EC No.EU chemical inventory number
255-490-0
DTXSIDUS EPA chemical ID
DTXSID60885734
DTXCIDUS EPA compound ID
DTXCID001025097
IUPAC
(4R)-1-Hexadecanoyl-4-(hexadecanoyloxy)-L-proline
Molecular formula
C37H69NO5
Molecular weight
607.961 g/mol

What products actually use it for

What the 7 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Softener and conditioner5
  • Anti-static agent2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
  • Moderate or Mild Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to

Source: US EPA CompTox dashboard

Related literature

Linked databases 12

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