What is this ingredient?

미국 FDA 물질 등록 · UNII 3O695R5M1U · 등록명 Diphenyl Ether · 단일 화학물질

All ingredients

Ingredient Dictionary

DIPHENYL ETHER

Definition

US FDA substance register · UNII 3O695R5M1U · registered name Diphenyl Ether · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Listed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCE

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

DIPHENYL ETHERINCIBenzene, 1,1'-oxybis-Synonym

CAS No.chemical registry number: 101-84-8
EC No.EU chemical inventory number: 202-981-2
DTXSIDUS EPA chemical ID: DTXSID9021847
DTXCIDUS EPA compound ID: DTXCID701847

IUPAC: 1,1'-Oxydibenzene
Molecular formula: C12H10O
Molecular weight: 170.211 g/mol

Measured properties

Odour threshold: 0.1 ppm
Melting/freezing point: 26.865 ℃
Initial boiling point and range: 258 ℃(760mmHg)
Flash point: 115 ℃
Upper/lower flammability or explosive limits: 1.5 / 0.8 %
Vapour pressure: 2.7 ㎜Hg (25℃)
Water solubility: 0.002 g/100㎖ (25℃)
Vapour density: 5.9
Relative density: 1.08
n-Octanol/water partition coefficient (Kow): 4.21 (25 °C)
Auto-ignition temperature: 610 ℃
Decomposition temperature: -1466.63 (kcal/mol)
Viscosity: 2.6 (40℃)
Molecular weight: 170.2

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 80 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance69
Flavouring and nutrient4
Deodorizer3
Intermediate2
Flame retardant1
Heat transferring agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

5 skin studies and 2 eye studies are on record.

Classed as low3

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 7 studies

Classification not possible
Skin Sensitization · Screening
Category 3
Skin Irritation · Screening
Category 6.3B (Category 3)
Skin Irritation · Read Across
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: FIFRA: Pesticide Assessment Guidelines, Subdivision F; Hazard Evaluation : Human and Domestic Animals; Office of Pesticide Programs, U.S. Envi ronmental Protection Agency, Nov. 1982, Section 81-5, Primary Dermal Irritation Study according to other guideline: TSCA: Health Effects Test Guidelines; Office of Toxic Substances; Office of Pesticide and Toxic Substances; United States Environmental Protection Agency, August 1982; Acute Exposure, Primary Dermal Irritation according to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
Category 2B
Eye Irritation · Screening
Category 6.4A (Category 2A)
Eye Irritation · Read Across