Bis(3-aminopropyl)amine is a polyazaalkane.
Definition
Bis(3-aminopropyl)amine is a polyazaalkane. It has a role as a plant metabolite and an algal metabolite. It is a conjugate base of a bis(3-azaniumylpropyl)azanium.
Source: PubChem
US FDA substance register · UNII RN1144MGND · registered name DIPROPYLENETRIAMINE · single chemical substance
Cosmetic roles
Safety & regulatory references
Korea’s toxic-substance GHS classification: Danger · H302 (category 4) · H330 (category 1) · H314 (category 1) · +2 more
Restriction II/411 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 56-18-8
- EC No.EU chemical inventory number
- 200-261-2
- DTXSIDUS EPA chemical ID
- DTXSID0025440
- DTXCIDUS EPA compound ID
- DTXCID505440
- IUPAC
- N~1~-(3-Aminopropyl)propane-1,3-diamine
- Molecular formula
- C6H17N3
- Molecular weight
- 131.223 g/mol
Measured properties
- Appearance
- 3,3'-iminodipropylamine appears as a colorless liquid. Less dense than water. Flash point of 170 °F. Very irritating to skin and eyes, and may be toxic by ingestion. Used to make soaps, dyes, and pharmaceuticals. · Liquid
- Boiling point
- 465.1 °F at 760 mmHg (NTP, 1992) · 235 °C @760 [mm Hg]
- Melting point
- 5.9 °F (NTP, 1992) · -14 °C
- Solubility
- Soluble (>=10 mg/ml) (NTP, 1992)
- Density
- 0.9307 at 68 °F (NTP, 1992) - Less dense than water, will float · 0.938 @25 °C
- pH
- 12 (100 g/L, 20℃)
- Melting/freezing point
- -14 ℃
- Initial boiling point and range
- 241 ℃
- Flash point
- 80 ℃(closed cup)
- Vapour pressure
- 0.03 ㎜Hg(20℃)
- Water solubility
- 1000000 ㎎/ℓ(25℃)
- Relative density
- 0.93 (20℃)
- n-Octanol/water partition coefficient (Kow)
- -1.15 (25℃)
- Viscosity
- 9.07 cP(20 °C)
- Molecular weight
- 131.221
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Intermediate1
- pH regulating agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 1 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 6 studies
- Skin Corr. 1A
Skin Irritation · Authoritative - Skin Sens. 1
Skin Sensitization · Authoritative - High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Category 1
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Category 1
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Linked databases 17
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese