Etidronate disodium is an organic sodium salt resulting from the replacement of two protons from etidronic acid (one from from each of the phosphonic acid groups) by sodium ions.
定义
Etidronate disodium is an organic sodium salt resulting from the replacement of two protons from etidronic acid (one from from each of the phosphonic acid groups) by sodium ions. It has a role as an antineoplastic agent, a chelator and a bone density conservation agent. It contains an etidronic acid(2-).
来源: PubChem
美国FDA 物质登记 · UNII M16PXG993G · 登记名称 Etidronate Disodium · 单一化学物质
化妆品中的作用
安全与法规参考
- 限用
- 韩国 · 中国
来源: 韩国食药处 化妆品法规信息
阿根廷 · 巴西
- Field of application and/or use : (a) Products for hair care (b) Soaps
- Maximum concentration permitted at final product : a.- 1.5% (calculated as Etidronic Acid) b.- 0.2% (calculated as Etidronic Acid)
东盟
- Field of application and/or use : (a) Hair-care (b) Soap
- Maximum authorised concentration in the finished cosmetic product : (a) 1.5% expressed as etidronic acid (b) 0.2% expressed as etidronic acid
欧盟
- Product Type, body parts : (a) Hair product (b) Soap
- Maximum concentration in ready for use preparation : (a) 1.5% (as etidronic acid) (b) 0.2% (as etidronic acid)
来源: 韩国食药处 化妆品法规信息
未列入韩国有毒物质 GHS 分类 · 现有化学物质
Restriction III/53 · Other restriction: ban substances that deplete the ozone layer
来源: 欧盟 CosIng 成分清单
Reviewed by CIR: Final Report: Safety Assessment of Etidronic Acid and Its Salts as Used in Cosmetics
来源: 美国CIR 安全性评估
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 7414-83-7
- EC No.欧盟化学品目录编号
- 231-025-7
- DTXSID美国EPA化学品编号
- DTXSID1029671
- DTXCID美国EPA化合物编号
- DTXCID609671
- IUPAC
- Disodium (1-hydroxyethane-1,1-diyl)bis[hydrogen (phosphonate)]
- 分子式
- C2H6Na2O7P2
- 分子量
- 249.99 g/mol
实测物性
- 性状
- 固体
- 颜色
- 白色
- 气味
- 无臭
- 分子量
- 252.01
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: 韩国安全保健公团 安全数据表
产品实际使用的用途
相关文献
- [Congenital osteoma of the skin. Attempt at diphosphonate therapy]. · 1986
- HLA antigens in lichen scterosus et atro‐phicus · 1985
- Disodium etidronate therapy for dystrophic cutaneous calcification. · 1975
- Calcinosis universalis: a rare diagnosis. · 2005
- P28 Recalcitrant exuberant digital calcinosis cutis in a patient of CREST syndrome - A case report · 2022