Disperse Blue 1 can cause cancer according to The World Health Organization's International Agency for Research on Cancer (IARC).
Definition
Disperse Blue 1 can cause cancer according to The World Health Organization's International Agency for Research on Cancer (IARC).
Source: PubChem
US FDA substance register · UNII 2429NAZ8WH · registered name DISPERSE BLUE 1 · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- Argentina · ASEAN · Brazil · China · European Union · South Korea · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
EU Cosmetics Regulation, Annex II (prohibited substances), entry 700
Restriction II/700
Source: EU CosIng ingredient list
Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2007-2010
Reviewed by CIR: Final Report on the Safety Assessment of Disperse Blue 1
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name 分散青1: 本品は、次の化学式で表される頭髪用染料である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 2475-45-8
- EC No.EU chemical inventory number
- 219-603-7
- DTXSIDUS EPA chemical ID
- DTXSID7020188
- DTXCIDUS EPA compound ID
- DTXCID10188
- IUPAC
- 1,4,5,8-Tetraaminoanthracene-9,10-dione
- Molecular formula
- C14H12N4O2
- Molecular weight
- 268.276 g/mol
Measured properties
- Melting/freezing point
- 331 ℃
- Vapour pressure
- 0.0000000108 ㎜Hg
- Water solubility
- 0.03 ㎎/ℓ (at 25℃)
- n-Octanol/water partition coefficient (Kow)
- 2.98
- Molecular weight
- 268.3
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Dye1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 6 studies
- Skin Irrit. 2
Skin Irritation · Authoritative - Classification not possible
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Skin Sens. 1
Skin Sensitization · Authoritative - Eye Dam. 1
Eye Irritation · Authoritative - Classification not possible
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Final Report on the Safety Assessment of Disperse Blue 1 · 1995
- Immune and epithelial responses to textile dyes: the role of chemical structure in toxicity · 2026
- Impaired cell viability and mitochondrial respiration by disperse textile dyes · 2025
- Annual Review of Cosmetic Ingredient Safety Assessments: 2007-2010 · 2011
Linked databases 24
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- IARC carcinogen classification
- JCIA labelling names (Japan)
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports 2
- Wikidata