4-(4-nitrophenylazo)aniline is azobenzene substituted at the phenyl 4-positions by an amino and a nitro group.
Definition
4-(4-nitrophenylazo)aniline is azobenzene substituted at the phenyl 4-positions by an amino and a nitro group. It has a role as a dye and an allergen. It is a member of azobenzenes and a primary arylamine. It is functionally related to an azobenzene.
Source: PubChem
US FDA substance register · UNII B7J3O076OT · registered name DISPERSE ORANGE 3 · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- Argentina · ASEAN · Brazil · China · European Union · South Korea · Taiwan · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
EU Cosmetics Regulation, Annex II (prohibited substances), entry 1281
Restriction II/1281
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 730-40-5
- EC No.EU chemical inventory number
- 211-984-8
- DTXSIDUS EPA chemical ID
- DTXSID7061061
- DTXCIDUS EPA compound ID
- DTXCID4047460
- IUPAC
- 4-[(4-Nitrophenyl)diazenyl]aniline
- Molecular formula
- C12H10N4O2
- Molecular weight
- 242.238 g/mol
Measured properties
- Appearance
- solid
- Melting/freezing point
- 215 ℃
- Water solubility
- 0.34 ㎎/ℓ (at 25C)
- n-Octanol/water partition coefficient (Kow)
- 3.590 (est.)
- Decomposition temperature
- 200 ℃
- Molecular weight
- 242.24
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Dye1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Sh
Skin Sensitization · Authoritative - SkinSens1
Skin Sensitization · QSAR Predicted
Source: US EPA CompTox dashboard
Related literature
- High frequency of simultaneous sensitivity to Disperse Orange 3 in patients with positive patch tests to para‐phenylenediamine · 2003
- Sensitization to Disperse Dyes in a Patch Test Population Over a Five-Year Period · 2002
- Hand dermatitis as an unsuspected presentation of textile dye contact sensitivity · 2002
- Frequency of textile dye and resin sensitization in patients with contact dermatitis in Israel · 2002
- Skin allergy from exposure to alloys of chromium · 1998
Linked databases 22
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem
- Taiwan FDA cosmetic ingredients
- Tlooto literature search 2 3 4 5
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Chinese