Definition
US FDA substance register · UNII B40A12D0GL · registered name DISTEARYL THIODIPROPIONATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Final Safety Assessment of Thiodipropionic Acid and its Dialkyl Esters as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 693-36-7
- EC No.EU chemical inventory number
- 211-750-5
- DTXSIDUS EPA chemical ID
- DTXSID3027299
- DTXCIDUS EPA compound ID
- DTXCID407299
- IUPAC
- Dioctadecyl 3,3'-sulfanediyldipropanoate
- Molecular formula
- C42H82O4S
- Molecular weight
- 683.17 g/mol
Measured properties
- Appearance
- CBI, Dry Powder, Other Solid, Large Crystals · White solid, [Hawley] White paste, [MSDSonline]
- Boiling point
- BP: 250 °C at 1 mm Hg · Boiling Point: >300 °C, decomposes at 300 °C
- Melting point
- 61 °C
- Solubility
- Insoluble in water · Water solubility: <0.001 g/L at 20 °C
- Density
- 1.027 g/cu cm at 25 °C
- Colour
- white
- Melting/freezing point
- 64~67 ℃
- Flash point
- 257 ℃
- Vapour pressure
- 0.00066 ㎩(20℃)
- Vapour density
- (23.6)
- n-Octanol/water partition coefficient (Kow)
- (&, gt, 6 at 20℃ est.)
- Auto-ignition temperature
- 380 ℃
- Molecular weight
- 683.18
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 36 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Antioxidant19
- Heat stabilizer4
- Lubricating agent4
- Processing aids not otherwise specified4
- pH regulating agent2
- UV stabilizer2
- Chemical reaction regulator1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) (1981) according to EU Method B.6 (Skin Sensitisation) 84/449/EEC B.6 (1984) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to other guideline: Hazardous-Substances Regulations under the U.S. Federal Hazardous Substances Labelling Act Sect. 191.11 (February 1965). according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
Linked databases 15
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search 2
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata