Ingredient Dictionary

DM HYDANTOIN

5,5-Dimethylhydantoin is an imidazolidine-2,4-dione.

Definition

5,5-Dimethylhydantoin is an imidazolidine-2,4-dione.

Source: PubChem

US FDA substance register · UNII 34032MQ9RO · registered name 5,5-Dimethylhydantoin · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Adjusts thicknessVISCOSITY CONTROLLINGSoftens hairHAIR CONDITIONING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Report Terminated: DM Hydantoin (not used in cosmetics and personal care products)

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Names & identifiers

DM HYDANTOININCI디엠하이단토인Korean label name (MFDS standard)2,4-Imidazolidinedione, 5,5-dimethyl-Synonym

CAS No.chemical registry number: 77-71-4
EC No.EU chemical inventory number: 201-051-3
DTXSIDUS EPA chemical ID: DTXSID5021754
DTXCIDUS EPA compound ID: DTXCID601754

IUPAC: 5,5-Dimethylimidazolidine-2,4-dione
Molecular formula: C5H8N2O2
Molecular weight: 128.131 g/mol

Measured properties

Appearance: Large Crystals, Liquid · White solid, [Hawley] White odorless crystalline powder, [Alfa Aesar MSDS]
Boiling point: Sublimes
Melting point: 178 °C
Solubility: Very soluble in ethanol, ether, acetone, benzene, chloroform, soluble in DMSO
Dissociation constant: pKa = 9.19
Colour: white
pH: 4
Melting/freezing point: 178 ℃
Flash point: 193 ℃
Flammability (solid, gas): flammable
Vapour pressure: 0.0000028 ㎜Hg (25℃ (est))
Water solubility: 100000 ㎎/ℓ (10℃)
Vapour density: 4.42
Relative density: 0.589 (@ 25 ℃)
n-Octanol/water partition coefficient (Kow): -0.48
Auto-ignition temperature: 364 ℃
Molecular weight: 128.15

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Ion exchange agent2
Softener and conditioner1
Processing aids not otherwise specified1
Surfactant (surface active agent)1
Viscosity modifier1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 1 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 5 studies

Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
Category 6.3B (Category 3)
Skin Irritation · Read Across
Category 6.5B (Category 1)
Skin Sensitization · Read Across
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to