Ingredient Dictionary

DODECENE

1-dodecene is an alkene that is dodecane containing one double bond at position 1.

Definition

1-dodecene is an alkene that is dodecane containing one double bond at position 1. It is an intermediate used in the production of lubricants and surfactants. It has a role as a mammalian metabolite and a human metabolite. It is a volatile organic compound and a dodecene.

Source: PubChem

US FDA substance register · UNII WYE669F3GR · registered name 1-Dodecene · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Base that dissolves other ingredientsSOLVENTAdjusts thicknessVISCOSITY CONTROLLINGListed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCE

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ドデセン: 本品は、次の化学式で表される不飽和炭化水素である。

Source: JCIA labelling names (Japan)

Names & identifiers

DODECENEINCI도데센Korean label name (MFDS standard)1-DodeceneSynonymドデセンJapanese labelling name

CAS No.chemical registry number: 112-41-4
EC No.EU chemical inventory number: 203-968-4
DTXSIDUS EPA chemical ID: DTXSID5026914
DTXCIDUS EPA compound ID: DTXCID306914

IUPAC: Dodec-1-ene
Molecular formula: C12H24
Molecular weight: 168.324 g/mol

Measured properties

Appearance: 1-dodecene appears as a clear colorless liquid with a mild, pleasnat odor. Insoluble in water and floats on water. Harmful or fatal by ingestion. Inhalation of vapors may irritate and damage lungs. High concentrations may have a narcotic effect. · Liquid, CBI
Odour: MILD, PLEASANT
Boiling point: 415 °F at 760 mmHg (USCG, 1999) · 213.8 °C
Melting point: -31 °F (USCG, 1999) · -35.2 °C
Solubility: Insoluble in water, sol in ethanol, ethyl ether, and acetone · Solubility in water: none
Density: 0.758 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.7584 g/cu cm @ 20 °C
Viscosity: 1.72 sq mm/s @ 20 °C · 1.72 ㎟/s
Colour: colourless
Melting/freezing point: -36~-31 ℃
Initial boiling point and range: 208~216 ℃
Flash point: 77 ℃((c.c.))
Upper/lower flammability or explosive limits: 0.62 / 5.42 %
Vapour pressure: 0.159 ㎜Hg ( (25 ℃))
Vapour density: 5.8-5.81
Relative density: 0.7584-0.76
n-Octanol/water partition coefficient (Kow): 6.10
Auto-ignition temperature: 225 ℃
Molecular weight: 168.31

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 23 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Lubricating agent3
Viscosity modifier3
Deodorizer2
Processing aids not otherwise specified2
Chemical reaction regulator2
Intermediate2
Monomers1
Diluent1

7 other uses

Solvent1
Degradant/impurity (EPA)1
Surfactant (surface active agent)1
Fuel1
Elasticizer1
Defoamer1
Flavouring and nutrient1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

18 skin studies and 7 eye studies are on record.

Classed as highly irritating5Classed as moderate3Classed as low30

The studies disagree (the most common conclusion covers 13%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 25 studies

Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to other guideline: 16 CFR 1500.41 according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substance Labelling Act (FHSLA) according to
Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Magnusson and Kligman
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: U.S. EPA FIFRA (Pesticide Assessment Guidelines Subdivision F/TSCA (798.4470) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to EPA OTS 798.4470 (Acute Dermal Irritation) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labelling Act (FHSLA) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act (FHSLA) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to EPA OTS 798.4470 (Acute Dermal Irritation) according to
Category 2
Skin Irritation · Screening
Classification not possible
Skin Sensitization · Screening
Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Category 6.3A (Category 2)
Skin Irritation · Read Across
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labelling Act according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act (FHSLA) according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Register 28 (110), 6.6.1963. paragraph 191.12 Test for eye irritants. according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to
Not classified
Eye Irritation · Screening