1-dodecene is an alkene that is dodecane containing one double bond at position 1.
定义
1-dodecene is an alkene that is dodecane containing one double bond at position 1. It is an intermediate used in the production of lubricants and surfactants. It has a role as a mammalian metabolite and a human metabolite. It is a volatile organic compound and a dodecene.
来源: PubChem
美国FDA 物质登记 · UNII WYE669F3GR · 登记名称 1-Dodecene · 单一化学物质
化妆品中的作用
溶解其他成分的基质SOLVENT调节黏度VISCOSITY CONTROLLING登记为香料组成物质（并非表示其增香）FRAGRANCE
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
详细资料——标示名称、识别编号、物性、试验记录、文献
官方标示名称和定义
日本化妆品工业联合会标示名称 ドデセン: 本品は、次の化学式で表される不飽和炭化水素である。
来源: 日本化妆品工业联合会标示名称
别名和识别信息
DODECENEINCI도데센韩国标示名称（食药处标准名）1-Dodecene同义名ドデセン日本标示名称
- CAS No.化学物质登记号
- 112-41-4
- EC No.欧盟化学品目录编号
- 203-968-4
- DTXSID美国EPA化学品编号
- DTXSID5026914
- DTXCID美国EPA化合物编号
- DTXCID306914
- IUPAC
- Dodec-1-ene
- 分子式
- C12H24
- 分子量
- 168.324 g/mol
实测物性
- 性状
- 1-dodecene appears as a clear colorless liquid with a mild, pleasnat odor. Insoluble in water and floats on water. Harmful or fatal by ingestion. Inhalation of vapors may irritate and damage lungs. High concentrations may have a narcotic effect. · Liquid, CBI
- 气味
- MILD, PLEASANT
- 沸点
- 415 °F at 760 mmHg (USCG, 1999) · 213.8 °C
- 熔点
- -31 °F (USCG, 1999) · -35.2 °C
- 溶解性
- Insoluble in water, sol in ethanol, ethyl ether, and acetone · Solubility in water: none
- 密度
- 0.758 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.7584 g/cu cm @ 20 °C
- 黏度
- 1.72 sq mm/s @ 20 °C · 1.72 ㎟/s
- 颜色
- 无色
- 熔点/凝固点
- -36~-31 ℃
- 初沸点和沸程
- 208~216 ℃
- 闪点
- 77 ℃((c.c.))
- 燃烧或爆炸范围上限/下限
- 0.62 / 5.42 %
- 蒸气压
- 0.159 ㎜Hg ( (25 ℃))
- 蒸气密度
- 5.8-5.81
- 比重
- 0.7584-0.76
- 正辛醇/水分配系数（Kow）
- 6.10
- 自燃温度
- 225 ℃
- 分子量
- 168.31
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 23 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Lubricating agent3
- Viscosity modifier3
- Deodorizer2
- Processing aids not otherwise specified2
- Chemical reaction regulator2
- Intermediate2
- Monomers1
- Diluent1
其余用途 7 项
- Solvent1
- Degradant/impurity (EPA)1
- Surfactant (surface active agent)1
- Fuel1
- Elasticizer1
- Defoamer1
- Flavouring and nutrient1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 18 项、眼部试验 7 项。
归类为刺激性高5 项归类为中等3 项归类为低30 项
各项试验结论不一（最多的结论占 13%），因此不能断定该成分有刺激性。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 25 项试验
- Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to other guideline: 16 CFR 1500.41 according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substance Labelling Act (FHSLA) according to - Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Magnusson and Kligman - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: U.S. EPA FIFRA (Pesticide Assessment Guidelines Subdivision F/TSCA (798.4470) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to EPA OTS 798.4470 (Acute Dermal Irritation) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labelling Act (FHSLA) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act (FHSLA) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to EPA OTS 798.4470 (Acute Dermal Irritation) according to - Category 2
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Category 6.3A (Category 2)
Skin Irritation · Read Across - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labelling Act according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act (FHSLA) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Register 28 (110), 6.6.1963. paragraph 191.12 Test for eye irritants. according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to - Not classified
Eye Irritation · Screening
来源: 美国EPA CompTox