Dodecyl gallate is a gallate ester.
Definition
Dodecyl gallate is a gallate ester.
Source: PubChem
US FDA substance register · UNII 45612DY463 · registered name DODECYL GALLATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Tentative Report: Amended Safety Assessment of Alkyl Gallates as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name 没食子酸ドデシル: 本品は、没食子酸（＊）とドデカノールのエステルであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 1166-52-5
- EC No.EU chemical inventory number
- 214-620-6
- DTXSIDUS EPA chemical ID
- DTXSID0048189
- DTXCIDUS EPA compound ID
- DTXCID5028164
- IUPAC
- Dodecyl 3,4,5-trihydroxybenzoate
- Molecular formula
- C19H30O5
- Molecular weight
- 338.444 g/mol
Measured properties
- Appearance
- White or creamy-white odourless solid · Solid
- Melting point
- Between 95 °C and 98 °C after drying at 90 °C for six hours · 96 - 97 °C
- Solubility
- Insoluble in water, freely soluble in ethanol and ether
- Vapour density
- 11.68
- Molecular weight
- 338.44
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Antioxidant3
- Processing aids not otherwise specified2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Category 6.3B (Category 3)
Skin Irritation · Read Across - Skin Sens. 1
Skin Sensitization · Authoritative - Category 6.5B (Category 1)
Skin Sensitization · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Contact hypersensitivity to selected excipients of dermatological topical preparations and cosmetics in patients with chronic eczema. · 2008
- Delayed Patch-Test Reading After 5 Days: An Update From the Mayo Clinic Contact Dermatitis Group · 2017
- Contact sensitization to cosmetic series of allergens in a general population in Beijing · 2014
- Ciclosporin ophthalmic emulsion – a novel therapy for benzyl alcohol‐associated eyelid dermatitis · 2008
- DETERMINATION OF ADDITIVES IN COSMETICS BY MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY · 2000
Linked databases 21
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese