Domiphen bromide is an aromatic ether.
Definition
Domiphen bromide is an aromatic ether.
Source: PubChem
US FDA substance register · UNII R4CY19YS7C · registered name DOMIPHEN BROMIDE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name 臭化ドミフェン: 本品は、次の化学式で表される４級アンモニウム塩である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 538-71-6
- EC No.EU chemical inventory number
- 208-702-0
- DTXSIDUS EPA chemical ID
- DTXSID5033468
- DTXCIDUS EPA compound ID
- DTXCID3013468
- IUPAC
- N,N-Dimethyl-N-(2-phenoxyethyl)dodecan-1-aminium bromide
- Molecular formula
- C22H40BrNO
- Molecular weight
- 414.472 g/mol
Measured properties
- Appearance
- Crystals
- Odour
- Mild characteristic odor
- Melting point
- 112-113 °C
- Solubility
- Freely soluble in water (100 g/100 mL), much less sol at low temps. Soluble in ethanol, acetone, ethyl acetate, chloroform, very slightly soluble in benzene
- pH
- pH of 10% solution: 6.42, 1% commercial product @ 25 °C: 5.5, of 0.1%: 6.8 · 6.42 (10% solution)
- Melting/freezing point
- 112.5 ℃(EXP)
- Vapour pressure
- 0.000000000031 ㎜Hg (25 deg C /Estimated/)
- Water solubility
- 500000 ㎎/ℓ (EXP)
- n-Octanol/water partition coefficient (Kow)
- 4.2 (EST)
- Molecular weight
- 414.47
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Pharmaceutical (EPA)1
- Deodorizer1
- Biocide1
Source: US EPA CompTox dashboard
Related literature
- Imidazoles and Quaternary Ammonium Compounds as Effective Therapies against (Multidrug-Resistant) Bacterial Wound Infections · 2024
- Combination of Miconazole and Domiphen Bromide Is Fungicidal against Biofilms of Resistant Candida spp · 2020
- Simultaneous quantitation of cationic disinfectants by high-performance liquid chromatography on a silica gel column using aqueous eluents · 2020
- Stressed degradation studies of domiphen bromide by LC‐ESI‐MS/MS identify a novel promising antimicrobial agent · 2018
- OBSERVATION ON THE BACTERIOSTAT EFFICACY AND TOXICITY STUDY OF THREE KINDS OF COMPOSITE BACTERIOSTAT AGENTS · 2013
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English